Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Recruiting 1Completed 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1CNS 1

Conditions

Multiple Myeloma 13Leukemia, Myeloid, Acute 12Neoplasm Metastasis 11Lymphoma 11Pancreatic Neoplasms 9Burkitt Lymphoma 8Breast Neoplasms 8Myelodysplastic Syndromes 7Glioma 7Leukemia, Lymphocytic, Chronic, B-Cell 6Colorectal Neoplasms 6Triple Negative Breast Neoplasms 5Sarcoma 5Prostatic Neoplasms 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Neuroblastoma 5Lymphoma, Non-Hodgkin 5Central Nervous System Neoplasms 5Carcinoma, Renal Cell 5Wilms Tumor 4Squamous Cell Carcinoma of Head and Neck 4Rhabdoid Tumor 4Ovarian Neoplasms 4Oropharyngeal Neoplasms 4Neuroectodermal Tumors, Primitive, Peripheral 4Medulloblastoma 4Lymphoma, T-Cell 4Lung Neoplasms 4Histiocytosis, Langerhans-Cell 4Hepatoblastoma 4

Interventions

Cyclophosphamide 10fludarabine 7pomalidomide 5pembrolizumab 5Dexamethasone 5daratumumab 4obinutuzumab 3glofitamab 3fludarabine phosphate 3abemaciclib 3Rituximab 3Melphalan 3Etoposide 3Bortezomib 3venetoclax 2tocilizumab 2palbociclib 2cemiplimab 2Temozolomide 2Oxaliplatin 2Nivolumab 2Mesna 2Letrozole 2Injections 2Immunotherapy, Adoptive 2Gemcitabine 2Biopsy 2zanubrutinib 1tislelizumab 1tipifarnib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Recurrence × Biopsy × 30 days × Clear all
NCT07416188 2026-06-05

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

National Institutes of Health Clinical Center (CC)

Phase 1/2 Recruiting
40 enrolled
CNS

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Nerve Tissue, Recurrence, Central Nervous System Neoplasms

NCT05564650 2026-05-19

Navitoclax in Relapsed or Refractory High-Risk Myelodysplastic Syndrome

Thomas Jefferson University

Phase 1 Completed
6 enrolled
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Recurrence, Leukemia, Myeloid, Acute

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