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Phase

Phase 2 24Phase NA 7Phase 1 2Phase EARLY_PHASE1 1Phase 4 1Phase 3 1

Status

Completed 2

Sponsor Class

OTHER 1NETWORK 1

Study Type

Interventional 2

Sponsor

Cancer Type

Lymphoid 2Sarcoma 1Other solid neoplasm 1Other hematologic neoplasm 1CNS 1

Conditions

Leukemia, Myeloid, Acute 22Myelodysplastic Syndromes 18Precursor Cell Lymphoblastic Leukemia-Lymphoma 13Lymphoma 12Leukemia 10Multiple Myeloma 9Hodgkin Disease 9Neuroblastoma 8Sarcoma 7Lymphoma, Non-Hodgkin 6Sarcoma, Ewing 5Primary Myelofibrosis 5Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 5Neoplasms, Plasma Cell 5Leukemia, Lymphocytic, Chronic, B-Cell 5Wilms Tumor 4Rhabdomyosarcoma 4Neuroectodermal Tumors, Primitive, Peripheral 4Medulloblastoma 4Lymphoma, Large B-Cell, Diffuse 4Leukemia, Myelomonocytic, Chronic 4Leukemia, Myelogenous, Chronic, BCR-ABL Positive 4Hematologic Neoplasms 4Graft vs Host Disease 4Congenital Abnormalities 4Central Nervous System Neoplasms 4Astrocytoma 4Testicular Neoplasms 3Retinoblastoma 3Optic Nerve Glioma 3

Interventions

Cyclophosphamide 41fludarabine 31Dexamethasone 27venetoclax 24Cytarabine 22Rituximab 16pembrolizumab 15fludarabine phosphate 14Filgrastim 12Etoposide 12Lenalidomide 11Vincristine 10Gemcitabine 10Azacitidine 10pomalidomide 9Interleukin-2 9Granulocyte Colony-Stimulating Factor 9Doxorubicin 9Calcium Dobesilate 9carfilzomib 8Topotecan 8Nivolumab 8Methotrexate 8Everolimus 8Decitabine 8Bortezomib 8Melphalan 7Cisplatin 7Vorinostat 6Injections 6

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Recurrence × Busulfan × Clear all
NCT01421173 2015-11-18

Vorinostat With Gemcitabine, Busulfan, and Melphalan With Stem Cell Transplant (SCT) in Relapsed or Refractory Lymphoid Malignancies

M.D. Anderson Cancer Center

Phase 1 Completed
78 enrolled
Lymphoid

Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Recurrence

NCT00006246 2009-10-07

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Pediatric Brain Tumor Consortium

Phase 1 Completed
28 enrolled
CNSLymphoidOther hematologic neoplasmOther solid neoplasmSarcoma

Familial ependymoma, Astrocytoma, Leukemia, Lymphoma, Medulloblastoma, Neoplasm Metastasis, Oligodendroglioma, Recurrence, Retinoblastoma, Sarcoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Meningeal Carcinomatosis

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