Clinical Trials

Leukemia, Recurrence, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT05751044 2025-09-16

HEM-iSMART B

Phase 1/2 Recruiting

26 enrolled

Leukemia, Recurrence, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT04050280 2025-05-01

CLAG-GO for Patients With Persistent, Relapsed or Refractory AML

Phase 2 Recruiting

39 enrolled

Recurrence, Leukemia, Myeloid, Acute

NCT03765541 2025-04-10

DEXAML-03

Phase 3 Terminated

73 enrolled

Recurrence, Leukemia, Myeloid, Acute

NCT06742463 2024-12-19

VHAG in Treating R/R T-ALL/LBL

Phase 2 Recruiting

50 enrolled

Lymphoma, Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05726110 2024-10-22

Selinexor in Combination With HAD or CAG Rregimens in Relapsed or Refractory Acute Myeloid Leukemia

Phase 3 Recruiting

50 enrolled

Recurrence, Leukemia, Myeloid, Acute

NCT06316960 2024-08-22

Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation

Phase 2 Recruiting

50 enrolled

Recurrence, Leukemia, Myeloid, Acute

NCT01186328 2024-02-01

EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL)

Phase 1 Terminated

6 enrolled 11 charts

Leukemia, Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT01614197 2023-07-27

A Trial of Temsirolimus With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphoma

16 enrolled 16 charts

Leukemia, Recurrence, Lymphoma, T-Cell, Peripheral, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05330377 2023-04-25

GM-CLAG in Relapsed/Refractory FLT3-mutated AML

Phase 1 Withdrawn

Recurrence, Leukemia, Myeloid, Acute

NCT01555541 2022-06-29

Intensive Consolidation and Stem Cell Mobilization Therapy Followed by Autologous Stem Cell Transplantation in High-risk Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

19 enrolled 18 charts

Lymphoma, Recurrence

NCT01411267 2022-04-04

AC220 for Children With Relapsed/Refractory ALL or AML

24 enrolled 14 charts

Leukemia, Leukemia, Myeloid, Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04722952 2021-12-03

PD-1 Inhibitor Combined With Azacytidine and Homoharringtonine，Cytarabine, G-CSF for Refractory or Relapsed AML

Phase 3 Unknown

30 enrolled

Leukemia, Recurrence, Leukemia, Myeloid, Acute

NCT01158885 2021-10-26

Clofarabine With Cytarabine for Patients With Minimal Residual Disease Positive Leukemia

2 enrolled 7 charts

Recurrence, Leukemia, Myeloid, Acute, Neoplasm, Residual, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02298166 2021-10-06

Study of Crenolanib in Combination With Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia and Activating FLT3 Mutations

Phase 3 Terminated

9 enrolled

Recurrence, Leukemia, Myeloid, Acute

NCT02249091 2021-08-25

A Phase II Study of Selinexor Plus Cytarabine and Idarubicin in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML)

42 enrolled 16 charts

Recurrence, Leukemia, Myeloid, Acute

NCT01861002 2021-06-09

A Phase I Study of 5-Azacytidine in Combination With Chemotherapy for Children With Relapsed or Refractory ALL or AML

15 enrolled 10 charts

Leukemia, Leukemia, Myeloid, Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00439296 2021-03-17

ABT-751 With Chemotherapy for Relapsed Pediatric ALL

Phase 1/2 Terminated

9 enrolled 12 charts

Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03661515 2020-05-20

FLAGINEXOR

16 enrolled

Recurrence, Leukemia, Myeloid, Acute

NCT01289457 2020-02-24

Clofarabine, Idarubicin, and Cytarabine (CIA) Versus Fludarabine, Idarubicin, and Cytarabine (FLAI) in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome

Phase 1/2 Completed

282 enrolled 13 charts

Leukemia, Recurrence, Leukemia, Myeloid, Acute

NCT00440726 2020-02-19

Bortezomib With Chemotherapy for Relapsed Pediatric Acute Lymphoblastic Leukemia (ALL)

Phase 1/2 Completed

31 enrolled 15 charts

Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00939653 2020-02-19

T2007-002 Clofarabine, Etoposide, Cyclophosphamide in Relapsed Acute Myelogenous Leukemia (AML)

6 enrolled 10 charts

Recurrence, Leukemia, Myeloid, Acute

NCT02652871 2019-11-15

LY2510924, Idarubicin and Cytarabine in Patients With Relapsed or Refractory Acute Myeloid Leukemia

36 enrolled

Leukemia, Recurrence, Leukemia, Myeloid, Acute

NCT02535806 2019-08-13

Four Drug Reinduction With Bortezomib for Relapsed or Refractory ALL or LL in Children and Young Adults

2 enrolled 11 charts

Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00928200 2019-02-19

Erwinase for Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) (IND 104224)

Phase 1 Terminated

1 enrolled 7 charts

Hypersensitivity, Leukemia, Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03207334 2018-10-22

iCare4: Genomic Signatures With Midostaurin in Acute Myeloid Leukemia (UF-HEM-004)

Phase 2 Withdrawn

MyeloidOther hematologic neoplasm

Recurrence, Leukemia, Myeloid, Acute

NCT02717884 2018-10-18

TRANSATRA

Phase 1/2 Unknown

60 enrolled

Myelodysplastic Syndromes, Recurrence, Leukemia, Myeloid, Acute

NCT01444742 2018-07-03

Clofarabine Plus Low-Dose Cytarabine for Patients With Higher-Risk Myelodysplastic Syndrome (MDS)

MyeloidOther hematologic neoplasm

81 enrolled 9 charts

Leukemia, Myelodysplastic Syndromes, Recurrence

NCT01692197 2018-07-03

E7070, Idarubicin and Cytarabine in Relapsed AML and High-Risk Myelodysplastic Syndromes

43 enrolled 11 charts

Leukemia, Recurrence, Leukemia, Myeloid, Acute

NCT00336583 2018-06-26

Etoposide, Methylprednisolone, High-dose Cytarabine and Oxaliplatin as 2nd Line Therapy for Non-Hodgkin's Lymphoma (NHL)

27 enrolled 8 charts

Lymphoma, Non-Hodgkin, Recurrence

NCT02718755 2018-06-26

Phase II Study of Fludarabine, Cytarabine (ARA-C) and Erwinase IV in Patients With Relapsed or Refractory Hematologic Malignancies

Phase 2 Withdrawn

Burkitt Lymphoma, Lymphoma, Recurrence, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myeloid, Acute, Lymphoma, B-Cell, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02983097 2018-01-19

R²-DHAP

Phase 1/2 Terminated

34 enrolled

Burkitt Lymphoma, Lymphoma, Recurrence, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Mantle-Cell

NCT00281879 2017-09-27

Donor Stem Cell Transplant or Donor White Blood Cell Infusions in Treating Patients With Hematologic Cancer

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cellSarcoma

200 enrolled 11 charts

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Blast Crisis, Burkitt Lymphoma, Hodgkin Disease, Leukemia, Leukemia, Hairy Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Leukemia, Myelomonocytic, Juvenile, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Dendritic Cell Sarcoma, Interdigitating, Primary Myelofibrosis

NCT01324180 2017-08-07

Vincristine, Dexamethasone, Doxorubicin, and PEG-asparaginase (VPLD) and Metformin for Relapsed Childhood Acute Lymphoblastic Leukemia (ALL)

14 enrolled

Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01449344 2017-03-07

(R-HAD)

Phase 3 Unknown

128 enrolled

Recurrence, Lymphoma, Mantle-Cell

NCT02784561 2016-05-27

Study of Busulfan and FLAG Conditioning Regimen for Allogeneic Peripheral Blood Stem Cell Transplantation

Phase 4 Unknown

80 enrolled

Leukemia, Recurrence

NCT01681537 2016-03-17

Lenalidomide Plus Chemotherapy for AML

36 enrolled

LymphoidMyeloidOther hematologic neoplasmOther neoplasmPlasma cellSarcoma

Recurrence, Leukemia, Myeloid, Acute

NCT00423826 2016-02-29

Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease

No longer available

Congenital Abnormalities, Immunoglobulin Light-chain Amyloidosis, Blast Crisis, Burkitt Lymphoma, Leukemia, Erythroblastic, Acute, Hodgkin Disease, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, Myelodysplastic Syndromes, Precancerous Conditions, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Acute, Leukemia, Promyelocytic, Acute, Leukemia, Myelomonocytic, Acute, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Lymphoma, Extranodal NK-T-Cell, Dendritic Cell Sarcoma, Interdigitating

NCT00003631 2016-01-25

Chemotherapy Plus Radiation Therapy in Treating Patients With Refractory or Relapsed Hodgkin's Lymphoma

118 enrolled 8 charts

Hodgkin Disease, Lymphoma, Recurrence

NCT02532192 2016-01-06

A Phase Ib Study of Belinostat With RDHAP Chemotherapy (Dexamethasone, Cytarabine, Cisplatinum) in Adults With Relapsed or Refractory Diffuse Large B-cell Lymphoma

Phase 1 Withdrawn

Lymphoma, Recurrence, Lymphoma, Large B-Cell, Diffuse

NCT01321346 2015-11-24

A Study Of Panobinostat In Children With Refractory Hematologic Malignancies

30 enrolled