Announcements Trials
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Phase

Phase 1 2

Status

Completed 2Unknown 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 1Lymphoid 1CNS 1

Conditions

Polycystic Ovary Syndrome 90Breast Neoplasms 21Insulin Resistance 18Obesity 14Prostatic Neoplasms 10Pancreatic Neoplasms 8Endometrial Neoplasms 7Infertility 6Anovulation 6Neoplasms 5Neoplasm Metastasis 5Colorectal Neoplasms 5Rectal Neoplasms 4Hyperandrogenism 4Weight Loss 3Squamous Cell Carcinoma of Head and Neck 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Lung Neoplasms 3Leukemia, Lymphocytic, Chronic, B-Cell 3Hyperinsulinism 3Head and Neck Neoplasms 3Diabetes Mellitus 3Carcinoma, Non-Small-Cell Lung 3Uterine Cervical Neoplasms 2Recurrence 2Rare Diseases 2Premature Birth 2Overweight 2Ovarian Neoplasms 2Multiple Myeloma 2

Interventions

Cyclophosphamide 67Dexamethasone 52Peripheral Blood Stem Cell Transplantation 37Lenalidomide 37Rituximab 35fludarabine phosphate 34Bortezomib 30Filgrastim 27Etoposide 27Cytarabine 25Carboplatin 25Busulfan 23Radiotherapy 22Melphalan 22Gemcitabine 22Cyclosporine 21pomalidomide 20fludarabine 20Whole-Body Irradiation 20Mycophenolic Acid 20Paclitaxel 19Methotrexate 18venetoclax 17Cisplatin 17pembrolizumab 16Calcium Dobesilate 16Bevacizumab 16Tacrolimus 14Antilymphocyte Serum 14Nivolumab 13

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Recurrence × Metformin × Clear all
NCT01528046 2023-01-13

Metformin in Children With Relapsed or Refractory Solid Tumors

H. Lee Moffitt Cancer Center and Research Institute

Phase 1 Completed
26 enrolled
CNS

Brain Neoplasms, Neoplasms, Recurrence

NCT01324180 2017-08-07

Vincristine, Dexamethasone, Doxorubicin, and PEG-asparaginase (VPLD) and Metformin for Relapsed Childhood Acute Lymphoblastic Leukemia (ALL)

H. Lee Moffitt Cancer Center and Research Institute

Phase 1 Completed
14 enrolled
LymphoidOther hematologic neoplasm

Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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