Announcements Trials
Browse Landscape

Phase

Phase 2 7Phase 3 5Phase 1/2 5Phase 1 2Phase NA 1Phase 2/3 1

Status

Withdrawn 2Completed 2Active not recruiting 1

Sponsor Class

INDUSTRY 3OTHER 2

Study Type

Interventional 5

Sponsor

Cancer Type

Plasma cell 3Other hematologic neoplasm 1Lymphoid 1

Conditions

Multiple Myeloma 9Recurrence 5Lymphoma, Large B-Cell, Diffuse 3Leukemia, Myeloid, Acute 3Sarcoma 2Glioblastoma 2Carcinoma, Non-Small-Cell Lung 2Waldenstrom Macroglobulinemia 1Vascular Neoplasms 1Triple Negative Breast Neoplasms 1Solitary Fibrous Tumors 1Solid Tumor Malignancy 1Smooth Muscle Tumor 1Sarcoma, Clear Cell 1Recurrent Squamous Cell Lung Carcinoma 1Pancreatic Neoplasms 1Osteosarcoma 1Neurofibrosarcoma 1Nerve Sheath Neoplasms 1Neoplasms, Plasma Cell 1Neoplasms, Adipose Tissue 1Neoplasm Metastasis 1Myoepithelioma 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1Lymphoma, Follicular 1Lymphoma, B-Cell, Marginal Zone 1Lymphoma, B-Cell 1Liposarcoma, Myxoid 1Liposarcoma 1

Interventions

Dexamethasone 33Cyclophosphamide 29venetoclax 18fludarabine 18Lenalidomide 16Bortezomib 16Cytarabine 13pembrolizumab 12Calcium Dobesilate 12Carboplatin 11fludarabine phosphate 10Rituximab 10pomalidomide 9Gemcitabine 9Nivolumab 8Azacitidine 7daratumumab 6carfilzomib 6blinatumomab 6Decitabine 6Bendamustine Hydrochloride 6selinexor 5obinutuzumab 5ibrutinib 5Vincristine 5Temozolomide 5Methotrexate 5Etoposide 5Cisplatin 5tafasitamab 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 1/2 × Recurrence × selinexor × Clear all
NCT02343042 2026-05-04

STOMP

Karyopharm Therapeutics Inc

Phase 1/2 Active not recruiting
300 enrolled
Plasma cell

Multiple Myeloma, Recurrence

NCT04607772 2025-10-03

Study of Selinexor in Combination With Backbone Treatments or Novel Therapies In Participants With Relapsed or Refractory (RR) Diffuse Large B-Cell Lymphoma (DLBCL)

Karyopharm Therapeutics Inc

Phase 1/2 Withdrawn
Lymphoid

Recurrence, Lymphoma, Large B-Cell, Diffuse

NCT02389543 2023-01-26

SLAM

Karyopharm Therapeutics Inc

Phase 1/2 Withdrawn
Plasma cell

Multiple Myeloma, Recurrence

NCT02186834 2023-01-04

Selinexor (KPT-330) and Liposomal Doxorubicin For Relapsed and Refractory Multiple Myeloma

H. Lee Moffitt Cancer Center and Research Institute

Phase 1/2 Completed
28 enrolled 10 charts
Plasma cell

Multiple Myeloma, Recurrence, Neoplasms, Plasma Cell

NCT02530476 2020-03-31

Phase I/II, Study of Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) + Sorafenib in Acute Myeloid Leukemia

M.D. Anderson Cancer Center

Phase 1/2 Completed
17 enrolled 14 charts
Other hematologic neoplasm

Leukemia, Recurrence, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

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