Clinical Trials

LymphoidOther hematologic neoplasm

9 enrolled

Hodgkin Disease, Lymphoma, Non-Hodgkin, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell

NCT06563804 2026-03-30

A Study to Evaluate S227928 as a Single Agent and in Combination With Venetoclax in Patients With R/R AML, MDS/AML, or CMML

MyeloidOther hematologic neoplasm

13 enrolled

Myelodysplastic Syndromes, Recurrence, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT06068400 2026-03-17

Clinical Study to Evaluate the Safety and Efficacy of CAR-T in the Treatment of Relapsed or Refractory Multiple Myeloma

Phase NA Terminated

1 enrolled

Multiple Myeloma, Recurrence

NCT05537766 2026-03-10

ZUMA-25

LymphoidOther hematologic neoplasm

19 enrolled 28 charts

Burkitt Lymphoma, Leukemia, Hairy Cell, Waldenstrom Macroglobulinemia, Recurrence

NCT05714345 2026-03-02

EXPAND

2 enrolled 8 charts

Lymphoma, Recurrence

NCT04362007 2026-02-25

A Phase I/II Study of ASTX660 in Patients With Relapsed or Refractory T-cell Lymphoma

8 enrolled 11 charts

Lymphoma, Recurrence

NCT03374085 2026-02-09

A Safety, PK and Efficacy Study of CC-92480 Monotherapy and in Combination With Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma (RRMM)

200 enrolled

Multiple Myeloma, Recurrence

NCT04809467 2026-02-04

topMIND

LymphoidOther hematologic neoplasm

54 enrolled 23 charts

Leukemia, Lymphoma, Non-Hodgkin, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell

NCT05787496 2026-01-28

A Safety, Tolerability and Efficacy Study of NC525 in Subjects With Advanced Myeloid Neoplasms

MyeloidOther hematologic neoplasm

28 enrolled 19 charts

Leukemia, Myelodysplastic Syndromes, Recurrence, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT03993379 2025-12-26

PROCLAIM: CX-072-002: Study of PD-L1 Probody Therapeutic CX-072 in Combination With Other Anticancer Therapy in Adults With Solid Tumors

3 enrolled 7 charts

Dermatologic

Diabetes Mellitus, Insulin-Dependent, 12, Melanoma, Neoplasms, Recurrence

NCT06304636 2025-11-24

DC15-MM-01

4 enrolled

Multiple Myeloma, Recurrence, Neoplasms, Plasma Cell

NCT03837509 2025-11-04

INCB001158 Combined With Subcutaneous (SC) Daratumumab, Compared to Daratumumab SC, in Relapsed or Refractory Multiple Myeloma

15 enrolled 15 charts

Multiple Myeloma, Recurrence

NCT05429502 2025-10-10

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

12 enrolled

CNSSarcoma

Glioma, Medulloblastoma, Neuroblastoma, Recurrence, Rhabdomyosarcoma

NCT04674748 2025-09-24

To Assess the Safety, Tolerability and Pharmacokinetics of INCB086550

3 enrolled

Neoplasm Metastasis, Recurrence

NCT05961839 2025-09-22

Study of SGR-2921 in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

66 enrolled

Recurrence, Leukemia, Myeloid, Acute

NCT05626322 2025-09-05

Effects of Maplirpacept (PF-07901801),Tafasitamab, and Lenalidomide in People With Relapsed or Refractory Diffuse Large B-cell Lymphoma

6 enrolled 17 charts

Lymphoma, Recurrence, Lymphoma, Large B-Cell, Diffuse

NCT04951778 2025-08-27

Study to Evaluate Safety and Tolerability of CC-91633 (BMS-986397) in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-Risk Myelodysplastic Syndromes

MyeloidOther hematologic neoplasm

56 enrolled

Myelodysplastic Syndromes, Recurrence, Leukemia, Myeloid, Acute

NCT05883449 2025-08-20

LuminICE-203

25 enrolled 21 charts

Hodgkin Disease, Recurrence, Lymphoma, T-Cell, Peripheral

NCT02675452 2025-07-09

AMG 176 First in Human Trial in Participants With Relapsed or Refractory Multiple Myeloma and Participants With Relapsed or Refractory Acute Myeloid Leukemia

Other hematologic neoplasmPlasma cell

141 enrolled 46 charts

Multiple Myeloma, Recurrence, Leukemia, Myeloid, Acute

NCT05274451 2025-07-01

A Study to Investigate LYL797 in Adults With Solid Tumors

BreastGynecologicThoracic

57 enrolled

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Fallopian Tube Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Recurrence, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05573035 2025-07-01

A Study to Investigate LYL845 in Adults With Solid Tumors

DermatologicGastrointestinalThoracic

39 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Recurrence, Colorectal Neoplasms

NCT05891197 2025-07-01

START

Terminated

10 enrolled

BreastGynecologicThoracic

NCT04789655 2025-05-31

Study of CC-96191 in Participants With Relapsed or Refractory Acute Myeloid Leukemia

45 enrolled

Leukemia, Myeloid, Recurrence, Leukemia, Myeloid, Acute

NCT04735575 2025-05-28

A Ph1/2 Study of EMB-06 in Participants With Relapsed or Refractory Myeloma

Other hematologic neoplasmPlasma cell

40 enrolled

Multiple Myeloma, Recurrence, Hematologic Neoplasms

NCT05038800 2025-05-21

MK-0482-002

13 enrolled 19 charts

Recurrence, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT05972720 2025-05-15

FIRCE-1

101 enrolled

Lymphoma, Lymphoma, Non-Hodgkin, Neoplasms, Recurrence, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse

NCT04464798 2025-04-29

A Dose Finding and Safety Study of CC-220, Alone and in Combination With an Anti-CD20 Monoclonal Antibody (mAb) in Subjects With Relapsed or Refractory Lymphomas

62 enrolled

Lymphoma, Recurrence

NCT05275673 2025-04-24

A Study of Sapanisertib in Relapsed/Refractory NFE2L2-Mutated and Wild-Type Squamous Non-Small Cell Lung Cancer

7 enrolled 11 charts

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Recurrence

NCT03486067 2025-04-17

Study of CC-93269, a BCMA x CD3 T Cell Engaging Antibody, in Participants With Relapsed and Refractory Multiple Myeloma

183 enrolled

Multiple Myeloma, Recurrence

NCT03690869 2025-04-08

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

57 enrolled 31 charts

CNS

Diffuse Intrinsic Pontine Glioma, Glioma, Recurrence, Central Nervous System Neoplasms

NCT03038230 2025-04-06

MCLA-117 in Acute Myelogenous Leukemia

80 enrolled

Recurrence, Leukemia, Myeloid, Acute, Neoplasm, Residual

NCT04975399 2025-03-24

Study to Evaluate the Safety and Tolerability of CC-92328 in Participants With Relapsed and/or Refractory Multiple Myeloma

26 enrolled

Multiple Myeloma, Recurrence

NCT04477291 2025-03-07

A Study of CG-806 in Patients With Relapsed or Refractory AML or Higher-Risk MDS

LymphoidMyeloidOther hematologic neoplasm

45 enrolled

Myelodysplastic Syndromes, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute

NCT05631574 2025-02-07

Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer

13 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Recurrence, Colorectal Neoplasms

NCT04887259 2025-01-27

Trial of LAVA-051 in Patients with Relapsed/refractory CLL, MM, or AML

LymphoidOther hematologic neoplasmPlasma cell

16 enrolled

Multiple Myeloma, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute

NCT01032070 2024-12-12

PETEY

25 enrolled 23 charts

Familial ependymoma, Ependymoma, Recurrence

NCT05588440 2024-12-05

A Clinical Study of ONCT-808 in Subjects With Relapsed or Refractory B-Cell Malignancies

9 enrolled 11 charts

Immune System Diseases, Immunoproliferative Disorders, Lymphatic Diseases, Lymphoma, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Recurrence, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Mantle-Cell

NCT04795713 2024-11-04

Study of MT-6402 in Subjects With Advanced Solid Cancer That Expresses PD-L1

64 enrolled

Head & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Recurrence

NCT03755154 2024-10-16

Study of a New Intravenous Drug, Called S65487, in Patients With Acute Myeloid Leukemia, Non Hodgkin Lymphoma, Multiple Myeloma or Chronic Lymphocytic Leukemia

LymphoidOther hematologic neoplasmPlasma cell

60 enrolled

Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute, Neoplasms, Plasma Cell

NCT04860466 2024-10-16

A Dose Finding Study of CC-96673 in Participants With Relapsed or Refractory Non-Hodgkin's Lymphoma

9 enrolled

Lymphoma, Non-Hodgkin, Recurrence

NCT03710915 2024-10-10

A Study of HG146 Capsule in Chinese Subjects with Relapsed and Refractory Multiple Myeloma

3 enrolled

Multiple Myeloma, Recurrence

NCT03220347 2024-10-08

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of CC-90010 in Subjects With Advanced Solid Tumors and Relapsed/Refractory Non-Hodgkin's Lymphomas

139 enrolled

Lymphoma, Non-Hodgkin, Neoplasms, Recurrence

NCT02099539 2024-09-26

QUILT-3.005: A Study of N-803 in Patients With Relapsed or Refractory Multiple Myeloma

19 enrolled 22 charts

Multiple Myeloma, Neoplasms, Recurrence

NCT04155424 2024-09-25

A Study of the Safety and Activity of Eculizumab in Pediatric Participants With Relapsing Neuromyelitis Optica Spectrum Disorder

Phase 2/3 Terminated

5 enrolled 15 charts

Demyelinating Diseases, Myelitis, Transverse, Neuromyelitis Optica, Optic Neuritis, Recurrence

NCT02978235 2024-09-05

A Dose Finding Study Followed by a Safety and Efficacy Study for Patients With Multiple Myeloma or Lymphoma