Announcements Trials
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Phase

Phase 1 2

Status

Completed 1Active not recruiting 1

Sponsor Class

NIH 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Genitourinary 2Thoracic 1Head & Neck 1Gynecologic 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Breast Neoplasms 81Carcinoma, Non-Small-Cell Lung 76Neoplasms 71Ovarian Neoplasms 68Neoplasm Metastasis 30Fallopian Tube Neoplasms 30Carcinoma, Ovarian Epithelial 29Lung Neoplasms 26Unspecified Adult Solid Tumor, Protocol Specific 24Triple Negative Breast Neoplasms 20Endometrial Neoplasms 20Esophageal Neoplasms 18Stomach Neoplasms 16Colorectal Neoplasms 14Squamous Cell Carcinoma of Head and Neck 13Head and Neck Neoplasms 13Solid Tumors 12Small Cell Lung Carcinoma 10Melanoma 10Pancreatic Neoplasms 9Uterine Cervical Neoplasms 8Prostatic Neoplasms 8Lymphoma, Non-Hodgkin 8Lymphoma, Large B-Cell, Diffuse 8Lymphoma 8Carcinoma, Renal Cell 8Carcinoma 8Brenner Tumor 8Urinary Bladder Neoplasms 7Precursor Cell Lymphoblastic Leukemia-Lymphoma 7

Interventions

Paclitaxel 2Kidney Transplantation 2Cyclophosphamide 2Azacitidine 2veliparib 1trifluridine tipiracil drug combination 1trebananib 1safinamide 1sacubitril and valsartan sodium hydrate drug combination 1rubitecan 1ripretinib 1regorafenib 1pomalidomide 1pevonedistat 1osimertinib 1mirabegron 1glucarpidase 1gamma-Glutamyl Hydrolase 1dabrafenib 1copanlisib 1belinostat 1belantamab mafodotin 1Whole-Body Irradiation 1Topotecan 1Taxes 1Sitagliptin Phosphate 1Rituximab 1Pharmacogenomic Testing 1Oxaliplatin 1Methotrexate 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Renal Insufficiency × Paclitaxel × Clear all
NCT01366144 2026-04-13

Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction

National Cancer Institute (NCI)

Phase 1 Active not recruiting
94 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Breast Neoplasms, Carcinoma, Transitional Cell, Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Unknown Primary, Ovarian Neoplasms, Testicular Neoplasms, Endometrial Neoplasms, Liver Failure, Renal Insufficiency

NCT01331941 2017-11-06

A Pharmacokinetic Study of AMG 386 in Cancer Subjects With Normal and Impaired Renal Function

Amgen

Phase 1 Completed
35 enrolled
Genitourinary

Kidney Diseases, Renal Insufficiency

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