Clinical Trials

25 enrolled

Phase NA Active not recruiting

Multiple Myeloma, Renal Insufficiency

NCT06408597 2026-03-18

Mannitol Versus Nitroglycerin for Kidney Injury Prevention in Robotic-assisted Radical Prostatectomy or Cystectomy

90 enrolled

Phase EARLY_PHASE1 Recruiting

Urinary Bladder Neoplasms, Prostatic Neoplasms, Renal Insufficiency, Acute Kidney Injury

NCT06142396 2026-03-12

Pilot Study Dara-CyBorD in Newly Diagnosed Multiple Myeloma Patients With Renal Failure

30 enrolled

Multiple Myeloma, Renal Insufficiency

NCT06623630 2026-03-11

Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal Function

Phase 1 Recruiting

16 enrolled

Multiple Myeloma, Renal Insufficiency

NCT06004661 2026-03-06

Study of Lutetium (177Lu) Vipivotide Tetraxetan in mCRPC Participants With Moderately and Severely Impaired and With Normal Renal Function

20 enrolled

Renal Insufficiency

NCT07029503 2026-02-24

SCARF-1

40 enrolled

Lymphoid

Heart Failure, Lymphoma, Follicular, Renal Insufficiency, Chronic, Renal Insufficiency

NCT07154901 2026-02-24

Investigation of the Effects of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of Opemalirsen (AZD2373)

Phase 1 Recruiting

50 enrolled

Lymphoid

Lymphoma, Follicular, Renal Insufficiency

NCT04240054 2026-01-28

VICD

41 enrolled

Phase NA Enrolling by invitation

Multiple Myeloma, Renal Insufficiency

NCT05443321 2026-01-23

Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes

1,006 enrolled

GastrointestinalGenitourinary

Arrhythmias, Cardiac, Asthma, Cardiovascular Diseases, Gastrointestinal Diseases, Heart Failure, Hematologic Diseases, Infections, Kidney Diseases, Nervous System Diseases, Rheumatic Diseases, Shock, Urologic Diseases, Critical Illness, Renal Insufficiency

NCT04561362 2025-11-14

Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies

Phase 1/2 Active not recruiting

329 enrolled

BreastGenitourinaryGynecologic

Urinary Bladder Neoplasms, Breast Neoplasms, Ovarian Neoplasms, Renal Insufficiency, Triple Negative Breast Neoplasms

NCT05992363 2025-07-24

TSTENT

Phase NA Recruiting

106 enrolled

Bites and Stings, Hydronephrosis, Neoplasms, Ureteral Obstruction, Renal Insufficiency

NCT01047735 2025-07-11

TRIABETES

Phase NA Active not recruiting

69 enrolled

Other

Behavior, Blindness, Body Weight, Cardiovascular Diseases, Death, Diabetes Mellitus, Diabetes Mellitus, Type 2, Digestive System Diseases, Disease, Hypertension, Inflammation, Insulin Resistance, Liver Diseases, Motor Activity, Myocardial Infarction, Neoplasms, Obesity, Obesity, Morbid, Weight Loss, Atherosclerosis, Renal Insufficiency, Non-alcoholic Fatty Liver Disease

NCT07053462 2025-07-08

CRISPR-Edited HLA Donor Kidney Transplant to Reduce Rejection Risk

Phase 1/2 Recruiting

90 enrolled

Carcinoma, Renal Cell, Kidney Failure, Chronic, Renal Insufficiency

NCT03101995 2025-05-28

Assessment of Gemcitabine as Chemoradiotherapy in Patients With Locally Advanced Carcinoma of Cervix and Renal Disease

Phase 1 Active not recruiting

18 enrolled

Gynecologic

Uterine Cervical Neoplasms, Renal Insufficiency

NCT04398745 2025-05-23

DREAMM12

36 enrolled

GenitourinaryPlasma cell

Kidney Failure, Chronic, Multiple Myeloma, Renal Insufficiency

NCT04823923 2025-02-12

IREKI

Phase NA Recruiting

60 enrolled

Kidney Neoplasms, Renal Insufficiency

NCT06337942 2025-02-12

Deceased Donor Bladder or Combined Kidney-bladder Transplantation: a Phase 0 First-in-human Study

Phase NA Recruiting

5 enrolled

Urinary Bladder Diseases, Urinary Bladder Neoplasms, Urinary Bladder, Neurogenic, Renal Insufficiency

NCT02301117 2024-09-05

A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment

43 enrolled

Carcinoma, Renal Cell, Kidney Diseases, Kidney Neoplasms, Urologic Diseases, Renal Insufficiency

NCT03814005 2024-09-05

A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

MyeloidOther hematologic neoplasm

17 enrolled 33 charts

Liver Diseases, Myelodysplastic Syndromes, Neoplasms, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Renal Insufficiency

NCT00113113 2024-08-02

Study of Rubitecan in Cancer Patients With Renal or Hepatic Dysfunction

54 enrolled

Liver Diseases, Neoplasms, Renal Insufficiency

NCT04352205 2024-07-01

Daratumumab-Based Therapy for the Treatment of Newly Diagnosed Multiple Myeloma With Kidney Failure

Phase 2 Terminated

17 enrolled

Phase NA Not yet recruiting

Multiple Myeloma, Renal Insufficiency

NCT04827290 2024-04-04

CKD AGE

66 enrolled

GenitourinaryLymphoid

Feeding Behavior, Kidney Failure, Chronic, Lymphoma, Follicular, Renal Insufficiency, Chronic, Renal Insufficiency

NCT04574050 2024-03-19

SELF-BREATHE RCT for Chronic Breathlessness

Phase NA Completed

52 enrolled

Classical hematologyOther

Anemia, Sickle Cell, Asthma, Cystic Fibrosis, Dyspnea, Neoplasms, Liver Failure, Lung Diseases, Interstitial, Pulmonary Disease, Chronic Obstructive, Renal Insufficiency

NCT04594161 2024-02-28

STONE

Phase NA Completed

204 enrolled

Bites and Stings, Calculi, Hydronephrosis, Infections, Kidney Calculi, Kidney Diseases, Neoplasm Metastasis, Pyelonephritis, Ureteral Obstruction, Urinary Calculi, Urologic Diseases, Renal Insufficiency, Urolithiasis, Pyonephrosis, Ureterolithiasis, Nephrolithiasis, Acute Kidney Injury

NCT05701735 2024-02-23

CECIL

Phase NA Unknown

45 enrolled

Gynecologic

Uterine Cervical Neoplasms, Renal Insufficiency

NCT02571036 2023-12-13

A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies

CNSDermatologicGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmSarcomaThoracic

282 enrolled

Mast Cell Activation Disorders, Carcinoma, Non-Small-Cell Lung, Glioma, Leukemia, Mast-Cell, Melanoma, Neoplasms, Germ Cell and Embryonal, Penile Neoplasms, Sarcoma, Mastocytosis, Systemic, Gastrointestinal Stromal Tumors, Renal Insufficiency

NCT02923947 2023-11-27

Study to Assess Osimertinib in Patients w/ Adv Solid Tumours & Normal Kidney Function or Severe Kidney Impairment

16 enrolled

Renal Insufficiency

NCT04656795 2023-05-15

PK Study in Subjects With Renal Impairment (Severe and if Required Mild & Moderate) Compared to Subjects With Normal Renal Function

32 enrolled

Lymphoid

Lymphoma, Follicular, Renal Insufficiency

NCT03639610 2023-03-10

BRIDGE

Phase 2 Terminated

35 enrolled 33 charts

Multiple Myeloma, Renal Insufficiency

NCT01575925 2022-11-04

POM Renal

25 enrolled

Multiple Myeloma, Renal Insufficiency

NCT01429038 2022-06-14

Mesenchymal Stem Cells After Renal or Liver Transplantation

Phase 1/2 Completed

40 enrolled

Fibrosis, Kidney Diseases, Liver Diseases, Neoplasms, Liver Failure, Liver Failure, Acute, Renal Insufficiency

NCT00634504 2022-06-06

LVPK

LymphoidOther hematologic neoplasmSarcoma

20 enrolled 9 charts

Leukemia, Lymphoma, Osteosarcoma, Renal Insufficiency

NCT05147493 2022-03-29

A Phase 2 Study of Isatuximab in Combination With Bortezomib, Cyclophosphamide and Dexamethasone Followed by Isatuximab and Lenalidomide Maintenance in Newly Diagnosed Patients With Multiple Myeloma and Severe Renal Impairment

Phase 2 Unknown

51 enrolled

Blood Protein Disorders, Hematologic Diseases, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Paraproteinemias, Renal Insufficiency, Neoplasms, Plasma Cell

NCT05298683 2022-03-28

A Phase 2 Study of Isatuximab in Combination With Pomalidomide and Dexamethasone in MM Patients Who Received One Prior Line of Therapy Containing Lenalidomide and a Proteasome Inhibitor

Phase 2 Unknown

108 enrolled

Blood Protein Disorders, Hematologic Diseases, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Paraproteinemias, Renal Insufficiency, Neoplasms, Plasma Cell

NCT02424851 2022-01-27

OPTIMAL

31 enrolled 13 charts

Multiple Myeloma, Renal Insufficiency, Chronic, Renal Insufficiency, Neoplasms, Plasma Cell

NCT02045017 2021-08-27

Efficacy and Safety of Pomalidomide and Dexamethasone in RRMM Patients With Renal Insufficiency

81 enrolled

Multiple Myeloma, Renal Insufficiency

NCT02668250 2021-08-26

OPTI-AGED

Phase NA Completed

2,495 enrolled

Alcoholism, Arrhythmias, Cardiac, Dementia, Diabetes Mellitus, Heart Failure, Ischemia, Neoplasms, Respiratory Insufficiency, Peripheral Vascular Diseases, Stroke, Pulmonary Disease, Chronic Obstructive, Renal Insufficiency

NCT03172884 2021-04-28

Study of Copanlisib in Hepatic or Renal Impairment

30 enrolled 20 charts

Hepatic Insufficiency, Renal Insufficiency

NCT01337752 2020-12-17

Study in Patients With Untreated Multiple Myeloma and Renal Insufficiency

9 enrolled

Multiple Myeloma, Renal Insufficiency

NCT00854139 2020-03-04

Combined Bone Marrow Transplantation (BMT) and Renal Transplant for Multiple Myeloma (MM) With End Stage Renal Disease (ESRD)

Other hematologic neoplasm

10 enrolled

GenitourinaryPlasma cell

Kidney Failure, Chronic, Multiple Myeloma, Renal Insufficiency

NCT02679131 2019-11-20

To Evaluate Safety and Pharmacokinetics of Belinostat in Patients Who Have Mild, Moderate and Severe Renal Impairment.

Phase 1 Terminated

18 enrolled

Recurrence, Hematologic Neoplasms, Renal Insufficiency

NCT00652626 2019-11-19

RENAL

31 enrolled 30 charts

LymphoidPlasma cell

Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Renal Insufficiency

NCT01447914 2019-08-28

Tivantinib in Treating Patients With Relapsed, or Relapsed and Refractory Multiple Myeloma