Announcements Trials
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Phase

Phase 1 3

Status

Completed 3

Sponsor Class

INDUSTRY 3

Study Type

Interventional 3

Sponsor

Cancer Type

Thoracic 3Breast 3Genitourinary 2Gastrointestinal 2

Conditions

Breast Neoplasms 12Carcinoma, Non-Small-Cell Lung 6Lung Neoplasms 5Breast Diseases 4Thoracic Neoplasms 3Respiratory Tract Neoplasms 3Neoplasms 3Lung Diseases 3Bronchial Neoplasms 3Neoplasms, Glandular and Epithelial 2Neoplasms by Histologic Type 2Melanoma 2Kidney Neoplasms 2Endocrine Gland Neoplasms 2Digestive System Neoplasms 2Respiratory Tract Diseases 1Ovarian Neoplasms 1Ovarian Diseases 1Neoplasms by Site 1Mammary Neoplasms, Animal 1Hodgkin Disease 1Fallopian Tube Neoplasms 1Carcinoma, Ovarian Epithelial 1Carcinoma, Bronchogenic 1Advanced Breast Cancer 1

Interventions

Carboplatin 8Pemetrexed 5pembrolizumab 4osimertinib 3entinostat 3Paclitaxel 3Erlotinib Hydrochloride 3selpercatinib 2pralsetinib 2efatutazone 2durvalumab 2Gemcitabine 2Cisplatin 2taletrectinib 1sotorasib 1repotrectinib 1patritumab 1necitumumab 1napabucasin 1ficlatuzumab 1exemestane 1cobimetinib 1ceralasertib 1camrelizumab 1alectinib 1aflutinib 1Patient Reported Outcome Measures 1Gefitinib 1130-nm albumin-bound paclitaxel 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
INDUSTRY × Respiratory Tract Neoplasms × entinostat × Clear all
NCT02897778 2022-04-28

Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors

Syndax Pharmaceuticals

Phase 1 Completed
30 enrolled
BreastGastrointestinalGenitourinaryThoracic

Breast Diseases, Breast Neoplasms, Bronchial Neoplasms, Carcinoma, Non-Small-Cell Lung, Digestive System Neoplasms, Endocrine Gland Neoplasms, Kidney Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Glandular and Epithelial, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT02909452 2022-01-25

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Syndax Pharmaceuticals

Phase 1 Completed
30 enrolled
BreastGastrointestinalGenitourinaryThoracic

Breast Diseases, Bronchial Neoplasms, Carcinoma, Non-Small-Cell Lung, Digestive System Neoplasms, Endocrine Gland Neoplasms, Kidney Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Glandular and Epithelial, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT01594398 2021-11-19

ENCORE110

Syndax Pharmaceuticals

Phase 1 Completed
14 enrolled
BreastThoracic

Breast Diseases, Breast Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

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