Announcements Trials
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Phase

Phase 1 1

Status

Active not recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Other solid neoplasm 1Genitourinary 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Carcinoma, Non-Small-Cell Lung 125Squamous Cell Carcinoma of Head and Neck 65Melanoma 64Parkinson Disease 4, Autosomal Dominant Lewy Body 52Lung Neoplasms 50Triple Negative Breast Neoplasms 47Neoplasm Metastasis 45Breast Neoplasms 41Neoplasms 38Colorectal Neoplasms 34Head and Neck Neoplasms 29Carcinoma, Renal Cell 29Ovarian Neoplasms 28Endometrial Neoplasms 28Carcinoma, Transitional Cell 22Urinary Bladder Neoplasms 21Stomach Neoplasms 17Carcinoma 17Pancreatic Neoplasms 15Uterine Cervical Neoplasms 14Recurrence 13Esophageal Neoplasms 13Sarcoma 11Hodgkin Disease 11Carcinoma, Squamous Cell 11Carcinoma, Hepatocellular 11Brain Neoplasms 11Cholangiocarcinoma 10Skin Neoplasms 9Esophageal Squamous Cell Carcinoma 9

Interventions

pembrolizumab 1LY2940680 1Cryotherapy 1Brachytherapy 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Retinoblastoma × pembrolizumab × 90 days × Clear all
NCT04483778 2026-04-28

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

Phase 1 Active not recruiting
68 enrolled
CNSDermatologicGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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