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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Other hematologic neoplasm 1Lymphoid 1Endocrine 1CNS 1

Conditions

Multiple Myeloma 43Precursor Cell Lymphoblastic Leukemia-Lymphoma 14Recurrence 7Lymphoma, Non-Hodgkin 6Burkitt Lymphoma 6Neoplasms, Plasma Cell 5Nausea 5Leukemia 5Vomiting 4Prostatic Neoplasms 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 4Neoplasms 4Lymphoma 4Neoplasm Metastasis 3Lymphoma, Large B-Cell, Diffuse 3Hematologic Neoplasms 3Amyloidosis 3Smoldering Multiple Myeloma 2Oligodendroglioma 2Lung Neoplasms 2Leukemia, Myeloid, Acute 2Leukemia, Biphenotypic, Acute 2Immunoglobulin Light-chain Amyloidosis 2Carcinoma, Non-Small-Cell Lung 2Breast Neoplasms 2Astrocytoma 2Waldenstrom Macroglobulinemia 1Uveal Melanoma 1Squamous Cell Carcinoma of Head and Neck 1Spinal Cord Neoplasms 1

Interventions

Topotecan 2Ifosfamide 2sargramostim 1omburtamab I-131 1etoposide phosphate 1antineoplaston AS 2-1 1antineoplaston A10 1Thiotepa 1Stem Cell Transplantation 1Radiotherapy, Intensity-Modulated 1Radiotherapy 1Radiosurgery 1Panobinostat 1Microarray Analysis 1Mesna 1Melphalan 1Immunohistochemistry 1Granulocyte Colony-Stimulating Factor 1Filgrastim 1Etoposide 1Dexamethasone 1Dasatinib 1Cyclophosphamide 1Carboplatin 1Calcium Dobesilate 1Busulfan 1Blotting, Western 13-(4-((4-chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid 12,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Terminated × Rhabdoid Tumor × Calcium Dobesilate × Clear all
NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

National Cancer Institute (NCI)

Phase 1 Terminated
129 enrolled
CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

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