Announcements Trials
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Phase

Phase 1 51Phase 2 30Phase 1/2 8Phase NA 5Phase EARLY_PHASE1 3Phase 3 3

Status

Completed 2Recruiting 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3

Conditions

Breast Neoplasms 182Neoplasms 115Prostatic Neoplasms 103Multiple Myeloma 85Glioblastoma 82Pancreatic Neoplasms 75Glioma 65Brain Neoplasms 60Lung Neoplasms 58Head and Neck Neoplasms 57Melanoma 54Colorectal Neoplasms 54Carcinoma, Non-Small-Cell Lung 53Leukemia, Myeloid, Acute 51Carcinoma, Hepatocellular 50Squamous Cell Carcinoma of Head and Neck 46Recurrence 46Ovarian Neoplasms 45Lymphoma 39Lymphoma, Non-Hodgkin 37Lymphoma, B-Cell 36Sarcoma 35Stomach Neoplasms 34Precursor Cell Lymphoblastic Leukemia-Lymphoma 34Neoplasm Metastasis 33Solid Tumor 31Hematologic Neoplasms 31Carcinoma, Renal Cell 30Polycystic Ovary Syndrome 27Burkitt Lymphoma 27

Interventions

etoposide phosphate 2Methotrexate 2Etoposide 2Vincristine 1Thiotepa 1Temozolomide 1Tamoxifen 1Mesna 1Leucovorin 1Isotretinoin 1Hydrocortisone 1Granulocyte Colony-Stimulating Factor 1Filgrastim 1Cyclophosphamide 1Cisplatin 1Celecoxib 1Carboplatin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase EARLY_PHASE1 × Interventional × Rhabdoid Tumor × Clear all
NCT06942039 2026-02-27

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

C17 Council

Phase EARLY_PHASE1 Recruiting
15 enrolled
CNS

Medulloblastoma, Neuroblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

NCT02905110 2025-03-25

Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors

The University of Texas Health Science Center, Houston

Phase EARLY_PHASE1 Completed
3 enrolled
CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Rhabdoid Tumor

NCT01737671 2018-01-19

Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study

M.D. Anderson Cancer Center

Phase EARLY_PHASE1 Completed
7 enrolled
CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Rhabdoid Tumor

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