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Phase

Phase 1/2 1

Status

Recruiting 30Active not recruiting 26Completed 11Not yet recruiting 6Terminated 2Suspended 1No longer available 1Enrolling by invitation 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1

Conditions

Neoplasms 18Leukemia, Myeloid, Acute 15Breast Neoplasms 14Glioblastoma 13Colorectal Neoplasms 13Prostatic Neoplasms 11Neoplasm Metastasis 10Carcinoma, Non-Small-Cell Lung 10Pancreatic Neoplasms 9Lung Neoplasms 9Glioma 8Precursor Cell Lymphoblastic Leukemia-Lymphoma 7Myelodysplastic Syndromes 7Multiple Myeloma 7Head and Neck Neoplasms 7Carcinoma, Renal Cell 7Carcinoma, Hepatocellular 7Hematologic Neoplasms 6Triple Negative Breast Neoplasms 5Rectal Neoplasms 5Ovarian Neoplasms 5Melanoma 5Uterine Cervical Neoplasms 4Colonic Neoplasms 4Brain Neoplasms 4Solid Tumor 3Small Cell Lung Carcinoma 3Sarcoma 3Recurrence 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3

Interventions

Vincristine 1Temozolomide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Suspended × Rhabdomyosarcoma × 1 year × Clear all
NCT04890093 2026-03-16

Vincristine and Temozolomide in Combination With PEN-866 for Adolescents and Young Adults With Relapsed or Refractory Solid Tumors

National Institutes of Health Clinical Center (CC)

Phase 1/2 Suspended
64 enrolled
Sarcoma

Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing

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