Announcements Trials
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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1

Conditions

Neoplasms 4Neoplasm Metastasis 3Squamous Cell Carcinoma of Head and Neck 2Ovarian Neoplasms 2Leukemia, Myeloid, Acute 2Colorectal Neoplasms 2Central Nervous System Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Breast Neoplasms 2Solid Tumor 1Small Cell Lung Carcinoma 1Rhabdomyosarcoma 1Prostatic Neoplasms 1Myelodysplastic Syndromes 1Microphthalmia, Isolated, with Coloboma 5 1Medulloblastoma 1Leukemia, Myelomonocytic, Chronic 1Hereditary Breast and Ovarian Cancer Syndrome 1Head and Neck Neoplasms 1Fanconi Anemia 1Endometrial Neoplasms 1Desmoplastic Small Round Cell Tumor 1Carcinoma, Squamous Cell 1Brain Neoplasms 1Anus Neoplasms 1Advanced Cancer 1

Interventions

Vincristine 25Cyclophosphamide 25Irinotecan 21Temozolomide 18Doxorubicin 16Radiotherapy 15Filgrastim 15Ifosfamide 14Dactinomycin 14Etoposide 11Vinorelbine 9Melphalan 9Magnetic Resonance Spectroscopy 9Granulocyte Colony-Stimulating Factor 9Radiation 8pegfilgrastim 7X-Rays 7Specimen Handling 7Sirolimus 7Topotecan 6Phantoms, Imaging 6Peripheral Blood Stem Cell Transplantation 6Gemcitabine 6cixutumumab 5Busulfan 5Biopsy 5temsirolimus 4irinotecan sucrosofate 4fludarabine 4etoposide phosphate 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Interventional × Rhabdomyosarcoma × prexasertib × Clear all
NCT04095221 2025-02-20

A Study of the Drugs Prexasertib, Irinotecan, and Temozolomide in People With Desmoplastic Small Round Cell Tumor and Rhabdomyosarcoma

Memorial Sloan Kettering Cancer Center

Phase 1/2 Completed
21 enrolled
Sarcoma

Rhabdomyosarcoma, Desmoplastic Small Round Cell Tumor

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