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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Genitourinary 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 26Burkitt Lymphoma 21Lymphoma, Large B-Cell, Diffuse 18Multiple Myeloma 16Lymphoma, Non-Hodgkin 14Leukemia, Myeloid, Acute 14Lymphoma 12Myelodysplastic Syndromes 11Lymphoma, Follicular 11Lymphoma, B-Cell 11Recurrence 10Ovarian Neoplasms 9Leukemia, Lymphocytic, Chronic, B-Cell 9Lymphoma, Mantle-Cell 8Leukemia 8Hodgkin Disease 8Pancreatic Neoplasms 7Leukemia, Myelogenous, Chronic, BCR-ABL Positive 7Hematologic Neoplasms 6Breast Neoplasms 6Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 5Neoplasms 5Leukemia, Myelomonocytic, Chronic 5Leukemia, Biphenotypic, Acute 5Anemia, Refractory, with Excess of Blasts 5Triple Negative Breast Neoplasms 4Stomach Neoplasms 4Sarcoma, Ewing 4Sarcoma 4Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 4

Interventions

selinexor 1pazopanib 1fludarabine phosphate 1fludarabine 1cabozantinib 1atezolizumab 1Specimen Handling 1Proton Therapy 1Mesna 1Ifosfamide 1Doxorubicin 1Cyclophosphamide 1Biopsy 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Sarcoma, Clear Cell × Cyclophosphamide × 30 days × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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