Announcements Trials
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Phase

Phase 2 2Phase 1 2Phase 2/3 1Phase 1/2 1

Status

Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 2Genitourinary 2Gastrointestinal 2Dermatologic 2CNS 2Other solid neoplasm 1

Conditions

Carcinoma, Non-Small-Cell Lung 177Neoplasm Metastasis 142Neoplasms 136Leukemia, Myeloid, Acute 128Colorectal Neoplasms 126Breast Neoplasms 115Ovarian Neoplasms 89Melanoma 88Prostatic Neoplasms 86Recurrence 84Multiple Myeloma 81Pancreatic Neoplasms 74Squamous Cell Carcinoma of Head and Neck 72Glioblastoma 72Lung Neoplasms 70Lymphoma, Non-Hodgkin 63Myelodysplastic Syndromes 60Triple Negative Breast Neoplasms 57Glioma 53Stomach Neoplasms 52Precursor Cell Lymphoblastic Leukemia-Lymphoma 49Endometrial Neoplasms 48Carcinoma, Renal Cell 47Small Cell Lung Carcinoma 46Lymphoma, Large B-Cell, Diffuse 44Brain Neoplasms 43Carcinoma, Hepatocellular 41Sarcoma 39Lymphoma, B-Cell 39Advanced Solid Tumors 39

Interventions

pembrolizumab 1fludarabine phosphate 1fludarabine 1Mesna 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Sarcoma, Clear Cell × 90 days × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT04483778 2026-04-28

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

Phase 1 Active not recruiting
68 enrolled
CNSDermatologicGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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