Announcements Trials
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Phase

Phase 2 7Phase 1 6Phase 1/2 3Phase NA 1Phase EARLY_PHASE1 1Phase 3 1

Status

Recruiting 3

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 3CNS 3Lymphoid 1Genitourinary 1Gastrointestinal 1

Conditions

Carcinoma, Non-Small-Cell Lung 52Neoplasms 28Neoplasm Metastasis 26Colorectal Neoplasms 26Recurrence 22Ovarian Neoplasms 22Pancreatic Neoplasms 21Prostatic Neoplasms 20Breast Neoplasms 20Squamous Cell Carcinoma of Head and Neck 19Melanoma 18Glioblastoma 16Lymphoma, Large B-Cell, Diffuse 14Lung Neoplasms 14Precursor Cell Lymphoblastic Leukemia-Lymphoma 13Multiple Myeloma 13Lymphoma, Non-Hodgkin 13Endometrial Neoplasms 13Triple Negative Breast Neoplasms 12Colonic Neoplasms 12Carcinoma, Renal Cell 11Stomach Neoplasms 10Leukemia, Myeloid, Acute 10Glioma 10Gastrointestinal Neoplasms 10Rectal Neoplasms 9Lymphoma, Follicular 9Lymphoma 9Head and Neck Neoplasms 9Small Cell Lung Carcinoma 8

Interventions

talazoparib 1irinotecan sucrosofate 1Temozolomide 1Eflornithine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1/2 × Sarcoma, Ewing × 30 days × Clear all
NCT06465199 2026-06-03

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

Milton S. Hershey Medical Center

Phase 1/2 Recruiting
289 enrolled
CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Neuroblastoma, Sarcoma, Ewing, Osteosarcoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT06395103 2026-06-01

MK-9999-01A

Merck Sharp & Dohme LLC

Phase 1/2 Recruiting
90 enrolled
CNSLymphoidSarcoma

Burkitt Lymphoma, Neuroblastoma, Sarcoma, Ewing, Lymphoma, Large B-Cell, Diffuse

NCT04901702 2026-05-19

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

St. Jude Children's Research Hospital

Phase 1/2 Recruiting
90 enrolled
CNSGastrointestinalGenitourinarySarcoma

Neoplasms, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

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