Announcements Trials
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Phase

Phase 1 2Phase 2 1

Status

Completed 3

Sponsor Class

INDUSTRY 3

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 3Thoracic 1Other solid neoplasm 1Other hematologic neoplasm 1Lymphoid 1

Conditions

Sarcoma 5Rhabdoid Tumor 4Lymphoma, Large B-Cell, Diffuse 4Lymphoma, Follicular 4Sarcoma, Synovial 3Lymphoma, Non-Hodgkin 3Lymphoma, B-Cell 3Wilms Tumor 2Sarcoma, Ewing 2Rhabdomyosarcoma 2Recurrence 2Osteosarcoma 2Neuroectodermal Tumors, Primitive, Peripheral 2Neuroblastoma 2Mesothelioma 2Medulloblastoma 2Histiocytosis, Langerhans-Cell 2Hepatoblastoma 2Glioma 2Ependymoma 2Central Nervous System Neoplasms 2Xanthogranuloma, Juvenile 1Prostatic Neoplasms 1Ovarian Neoplasms 1Neurofibrosarcoma 1Nerve Sheath Neoplasms 1Lymphoma, Mantle-Cell 1Lymphoma, B-Cell, Marginal Zone 1Inhibition, Psychological 1Hodgkin Disease 1

Interventions

pazopanib 4tazemetostat 3Doxorubicin 3cixutumumab 2Sorafenib 2Radiotherapy 2Radiation 2Interferon-gamma 2Ifosfamide 2Gemcitabine 2tremelimumab 1temsirolimus 1sapanisertib 1romidepsin 1pembrolizumab 1lorvotuzumab mertansine 1liposomal doxorubicin 1interferon gamma-1b 1indolepropanol phosphate 1durvalumab 1atezolizumab 1Watchful Waiting 1Surgical Procedures, Operative 1Sunitinib 1Rifampin 1Razoxane 1Ramucirumab 1Radiotherapy, Conformal 1Observation 1Leukapheresis 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Has results × Sarcoma, Synovial × tazemetostat × Clear all
NCT02601950 2025-06-22

A Study of Tazemetostat in Adult Participants With Soft Tissue Sarcoma

Ipsen

Phase 2 Completed
267 enrolled 25 charts 1 FDA
Sarcoma

Sarcoma, Sarcoma, Synovial

NCT04537715 2025-02-19

Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels

Ipsen

Phase 1 Completed
42 enrolled 39 charts
LymphoidOther hematologic neoplasmOther solid neoplasmSarcomaThoracic

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mesothelioma, Sarcoma, Sarcoma, Synovial, Lymphoma, Large B-Cell, Diffuse, Rhabdoid Tumor, Hematologic Neoplasms

NCT02601937 2024-10-03

EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma

Ipsen

Phase 1 Completed
109 enrolled 25 charts
Sarcoma

Sarcoma, Synovial, Rhabdoid Tumor

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