Announcements Trials
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Phase

Phase 1 2Phase 2 1Phase 1/2 1

Status

Completed 4No longer available 1

Sponsor Class

INDUSTRY 5

Study Type

Interventional 4Expanded_access 1

Sponsor

Cancer Type

Sarcoma 5Thoracic 3Other solid neoplasm 3Lymphoid 2Other hematologic neoplasm 1Genitourinary 1

Conditions

Lymphoma, Follicular 9Lymphoma, Large B-Cell, Diffuse 6Sarcoma, Synovial 5Sarcoma 4Rhabdoid Tumor 3Mesothelioma 3Lymphoma, B-Cell 3Recurrence 2Prostatic Neoplasms 2Lymphoma, Non-Hodgkin 2Lymphoma, Mantle-Cell 2Lymphoma, B-Cell, Marginal Zone 2Lymphoma 2Hematologic Neoplasms 2Neoplasms 1Multiple Myeloma 1Mesothelioma, Malignant 1Hepatic Impairment 1Desmoplastic Small Round Cell Tumor 1Chondrosarcoma 1Carcinoma, Renal Cell 1

Interventions

Cyclophosphamide 6tazemetostat 5fludarabine 4pembrolizumab 2soblidotin 1reolysin 1pazopanib 1drozitumab 1cixutumumab 1atezolizumab 1anlotinib 1Tablets 1Rosuvastatin Calcium 1Rifampin 1Ramucirumab 1Radiation 1Quality of Life 1Patient Reported Outcome Measures 1Molecular Diagnostic Techniques 1Midazolam 1Itraconazole 1Injections 1Immunotherapy, Adoptive 1Immunotherapy 1Imatinib Mesylate 1Ifosfamide 1Gemcitabine 1Drug Therapy 1Doxorubicin 1Docetaxel 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
INDUSTRY × Sarcoma, Synovial × tazemetostat × Clear all
NCT02875548 2025-11-04

TRuST

Ipsen

Phase 1/2 Completed
58 enrolled
LymphoidOther solid neoplasmSarcomaThoracic

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mesothelioma, Sarcoma, Synovial, Lymphoma, Large B-Cell, Diffuse

NCT02601950 2025-06-22

A Study of Tazemetostat in Adult Participants With Soft Tissue Sarcoma

Ipsen

Phase 2 Completed
267 enrolled 25 charts 1 FDA
Sarcoma

Sarcoma, Sarcoma, Synovial

NCT04537715 2025-02-19

Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels

Ipsen

Phase 1 Completed
42 enrolled 39 charts
LymphoidOther hematologic neoplasmOther solid neoplasmSarcomaThoracic

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mesothelioma, Sarcoma, Sarcoma, Synovial, Lymphoma, Large B-Cell, Diffuse, Rhabdoid Tumor, Hematologic Neoplasms

NCT02601937 2024-10-03

EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma

Ipsen

Phase 1 Completed
109 enrolled 25 charts
Sarcoma

Sarcoma, Synovial, Rhabdoid Tumor

NCT03874455 2024-03-22

Tazemetostat Expanded Access Program for Adults With Solid Tumors

Ipsen

No longer available
GenitourinaryOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Carcinoma, Renal Cell, Chondrosarcoma, Sarcoma, Sarcoma, Synovial, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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