Clinical Trials

Malignant mesenchymal tumor, Rhabdomyosarcoma, Sarcoma

NCT07049848 2026-05-22

SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma

50 enrolled

NCT07243626 2026-04-24

Efficacy and Safety of Envafolimab Plus Doxorubicin and Ifosfamide for Advanced Soft Tissue Sarcoma

25 enrolled

NCT04968106 2026-04-21

Bone Neoplasms, Breast Neoplasms, Glioma, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Non-Hodgkin, Neoplasm Metastasis, Neoplasms, Hereditary Sensory and Autonomic Neuropathies, Pancreatic Neoplasms, Sarcoma, Colorectal Neoplasms, Leukemia-Lymphoma, Adult T-Cell

NCT07125183 2026-02-05

Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

20 enrolled

Leiomyosarcoma, Sarcoma

NCT06835049 2025-12-30

TNT-HYPE

24 enrolled

Hyperthermia, Sarcoma

NCT04776525 2025-08-14

Sequential Neoadjuvant Chemotherapy in Soft Tissue Sarcoma

49 enrolled

NCT04874311 2025-08-13

TRUST

80 enrolled

Tertiary Lymphoid Structures, Neoplasm Metastasis, Sarcoma

NCT06277154 2025-07-24

MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma

Phase 2 Active not recruiting

148 enrolled

GynecologicSarcoma

Fibrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Sarcoma, Sarcoma, Synovial, Sarcoma, Endometrial Stromal, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous, Desmoplastic Small Round Cell Tumor

NCT03719430 2025-04-29

APX005M and Doxorubicin in Advanced Sarcoma

27 enrolled

Leiomyosarcoma, Liposarcoma, Sarcoma, Sarcoma, Synovial, Neurofibrosarcoma

NCT04996004 2024-12-11

TTI-621-03

76 enrolled 53 charts

Phase 2 Not yet recruiting

Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Sarcoma, Dermatofibrosarcoma

NCT06500091 2024-07-15

TQB2916 Injection Combined With Chemotherapy or Penpulimab Injection in the Treatment of Solid Tumors

54 enrolled

DermatologicSarcoma

Melanoma, Sarcoma

NCT04535713 2024-07-05

GALLANT: Metronomic Gemcitabine, Doxorubicin, Docetaxel and Nivolumab for Advanced Sarcoma

260 enrolled

NCT01514188 2024-05-29

Preliminary Efficacy and Safety of INNO-206 Compared to Doxorubicin in Advanced Soft Tissue Sarcoma

126 enrolled 13 charts

Neoplasm Metastasis, Sarcoma

NCT03056001 2023-11-18

Safety, Tolerability, and Efficacy of Doxorubicin and Pembrolizumab for Sarcoma

30 enrolled 22 charts

NCT02584309 2023-11-07

Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma

73 enrolled 11 charts

Fibrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Sarcoma, Sarcoma, Synovial, Dermatofibrosarcoma, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT03317457 2023-06-15

MEDISARC

103 enrolled

NCT04012827 2022-09-07

Apatinib Mesylate Combined With Doxorubicin and Ifosfamide in Advanced Soft-tissue Sarcoma

108 enrolled

NCT05138146 2021-11-30

A Phase 2 Clinical Study of Evaluation of Recombinant Anti-PD-1 Humanized Monoclonal Antibody Injection (609A) Combined With Doxorubicin Hydrochloride in the Treatment of Metastatic/Unresectable Non-specific Soft Tissue Sarcoma

70 enrolled

NCT04910126 2021-06-02

Camrelizumab Plus Doxorubicin for the First Line Treatment of Adcanced Soft Tissue Sarcoma

84 enrolled

Sarcoma, Neoplasms, Connective and Soft Tissue

NCT02448537 2021-03-03

A Phase II Multi-Strata Study of PM01183 as a Single Agent or in Combination With Conventional Chemotherapy in Metastatic and/or Unresectable Sarcomas

42 enrolled 11 charts

NCT03698227 2020-07-15

OlaReDo - Olaratumab and Rechallenge With Doxorubicin in Soft Tissue Sarcoma Patients

2 enrolled

NCT04356872 2020-07-14

The Combination of Sintilimab and AI (Doxorubicin, ADM/Ifosfamide, IFO) for the First Line Treatment of Select Type of Metastatic/Unresectable Soft Tissue Sarcoma

45 enrolled

NCT00061893 2019-02-15

Vinblastine, Celecoxib, and Combination Chemotherapy in Treating Patients With Newly-Diagnosed Metastatic Ewing's Sarcoma Family of Tumors

38 enrolled 10 charts

Sarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT02255110 2018-12-14

A Japanese Trial of TH-302 in Subjects With Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma

6 enrolled 6 charts

NCT00304083 2018-09-18

Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors

48 enrolled 10 charts

CNSSarcoma

Neurofibromatosis 1, Sarcoma, Neurofibrosarcoma

NCT00484341 2018-08-29

Phase II Study of NGR-hTNF in Combination With Doxorubicin in Patients Affected by Soft Tissue Sarcomas.

69 enrolled

NCT00089544 2018-04-13

Preoperative Thalidomide With Radiation Therapy For Patients With Low-Grade Primary Soft Tissue Sarcoma or Thalidomide With Radiation Therapy and Chemotherapy For Patients With High-Grade or Intermediate-Grade Primary Soft Tissue Sarcoma of the Arm, Leg, or Body Wall

23 enrolled 6 charts

NCT01055314 2017-08-29

Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma

175 enrolled 13 charts

Rhabdomyosarcoma, Sarcoma

NCT01861951 2017-08-21

EPAZ

120 enrolled

NCT00043979 2017-05-31

Stem Cell Transplantation in Patients With High-Risk and Recurrent Pediatric Sarcomas

60 enrolled 31 charts

Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Desmoplastic Small Round Cell Tumor

NCT00002601 2017-03-03

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Sarcoma

13 enrolled 8 charts

Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00002492 2016-12-15

Combination Chemotherapy in Treating Patients With Soft Tissue Sarcoma

NCT02812654 2016-06-24

Ifosfamide, Doxorubicin and Hypofractionated Radiotherapy in Neoadjuvant Sarcoma Treatment

70 enrolled

NCT01104298 2015-10-27

Doxorubicin vs. Trabectedin Plus Doxorubicin in Non Operable and/or Metastatic STS

115 enrolled

Sarcoma, Ichthyosis, X-Linked

NCT00019864 2015-06-08

Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma

100 enrolled

Sarcoma, Osteosarcoma, Cardiotoxicity

NCT00755261 2015-05-08

Phase II Study of Doxorubicin and Avastin® in Sarcoma.

4 enrolled 4 charts

NCT00544778 2014-08-28

Combination Chemotherapy and Dexrazoxane Followed by Surgery and Radiation Therapy in Treating Patients With Advanced Soft Tissue Sarcoma or Recurrent Bone Sarcoma

7 enrolled 2 charts

Sarcoma, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00410462 2014-08-08

Brostallicin or Doxorubicin as First-Line Therapy in Treating Patients With Relapsed, Refractory, or Metastatic Soft Tissue Sarcoma

118 enrolled

GynecologicSarcoma

Malignant mesenchymal tumor, Fibrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Ovarian Neoplasms, Rhabdomyosarcoma, Sarcoma, Sarcoma, Synovial, Sarcoma, Alveolar Soft Part, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT00002804 2014-07-25

Combination Chemotherapy, Surgery, and Radiation Therapy in Treating Children With Advanced Soft Tissue Sarcoma

43 enrolled

NCT00718484 2014-01-30

PICASSO

67 enrolled

NCT00002791 2014-01-24

Chemotherapy Plus Radiation Therapy Followed by Surgery in Treating Patients With Soft Tissue Sarcoma

NCT00025441 2013-12-04

Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors

GynecologicSarcoma

Malignant mesenchymal tumor, Hemangiopericytoma, Malignant, Chondrosarcoma, Fibrosarcoma, Hemangiosarcoma, Liposarcoma, Ovarian Neoplasms, Sarcoma, Neuroectodermal Tumors, Primitive, Peripheral, Desmoplastic Small Round Cell Tumor

NCT00002608 2013-07-10

Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors

CNSEndocrineGastrointestinalHead & NeckOther solid neoplasmSarcomaThoracic

30 enrolled

Familial ependymoma, Thyroid Cancer, Papillary, Mesothelioma, Malignant, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Medulloblastoma, Oligodendroglioma, Pheochromocytoma, Sarcoma, Thyroid Neoplasms, Central Nervous System Neoplasms, Adenocarcinoma, Follicular, Adrenocortical Carcinoma, Carcinoma, Medullary, Glioma, Subependymal, Gliosarcoma, Optic Nerve Glioma, Thyroid Carcinoma, Anaplastic

NCT00002993 2013-07-09

Combination Chemotherapy in Treating Patients With Recurrent or Advanced Cancer of the Uterus

30 enrolled

NCT01095926 2013-06-28

Doxo

CNSGenitourinaryLymphoidOther hematologic neoplasmSarcoma

101 enrolled

Neoplasms, Wilms Tumor, Neuroblastoma, Sarcoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Cardiotoxicity

NCT00017160 2013-06-27

Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Primary or Recurrent Sarcoma

Phase 2 Withdrawn

NCT00003667 2013-06-25

Combination Chemotherapy and Biological Therapy in Treating Patients With High-Risk Ewing's Sarcoma