Clinical Trials Browser

Interventional × Sarcoma × Topotecan × Clear all

NCT00638898 2025-03-20

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

Familial ependymoma, Astrocytoma, Brain Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Testicular Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT03709680 2025-01-14

Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors

Phase 2 Active not recruiting

128 enrolled

CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Bone Neoplasms, Medulloblastoma, Neoplasms, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Rhabdoid Tumor

NCT03600649 2023-11-21

Clinical Trial of SP-2577 (Seclidemstat) in Patients With Relapsed or Refractory Ewing or Ewing-related Sarcomas

Phase 1 Unknown

50 enrolled

Sarcoma

Histiocytoma, Angiomatoid Fibrous, Chondrosarcoma, Extraskeletal Myxoid, Fibroma, Myoepithelioma, Sarcoma, Sarcoma, Ewing, Liposarcoma, Myxoid, Sarcoma, Clear Cell, Desmoplastic Small Round Cell Tumor

NCT02357810 2022-06-07

Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas

Phase 2 Completed

178 enrolled 16 charts

Sarcoma

Liposarcoma, Sarcoma, Osteosarcoma

NCT02390843 2020-04-03

AflacST1402

Phase 1 Completed

13 enrolled

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Renal Cell, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Rhabdoid Tumor

NCT01492673 2019-10-29

Cyclophosphamide, Topotecan, and Bevacizumab (CTB) in Patients With Relapsed/Refractory Ewing's Sarcoma and Neuroblastoma

Phase 2 Completed

9 enrolled 9 charts

CNSSarcoma

Neuroblastoma, Sarcoma, Sarcoma, Ewing

NCT00379457 2013-08-12

Combination Chemotherapy in Treating Young Patients With Nonmetastatic Rhabdomyosarcoma

Phase 3 Unknown

600 enrolled

Sarcoma

Malignant mesenchymal tumor, Sarcoma

NCT00334867 2013-06-28

Combination Chemotherapy With or Without Topotecan in Treating Patients With Newly Diagnosed Localized Ewing's Sarcoma

Phase 3 Withdrawn

Sarcoma

Sarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00002515 2013-06-24

Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer

Phase 2 Completed

CNSGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther solid neoplasmSarcoma

Testicular Germ Cell Tumor, Burkitt Lymphoma, Chondrosarcoma, Fibrosarcoma, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lymphoma, Wilms Tumor, Neuroblastoma, Ovarian Neoplasms, Retinoblastoma, Sarcoma, Osteosarcoma, Testicular Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Dendritic Cell Sarcoma, Interdigitating, Desmoplastic Small Round Cell Tumor

NCT00003958 2013-06-17

Combination Chemotherapy in Treating Patients With Previously Untreated Rhabdomyosarcoma

Phase 3 Completed

702 enrolled

Sarcoma

Malignant mesenchymal tumor, Rhabdomyosarcoma, Sarcoma

NCT00003156 2013-04-11

Topotecan in Treating Patients With Recurrent or Refractory Cancer of the Uterus

Phase 2 Terminated

Sarcoma

NCT00842452 2013-04-05

Topotecan in Treating Patients With Gynecologic Cancer That Cannot Be Removed by Surgery

Phase 1 Completed

26 enrolled

GynecologicSarcoma

Carcinoma, Ovarian Epithelial, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Sarcoma, Vaginal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms

NCT00003745 2013-02-05