Announcements Trials
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Phase

Phase 1 3Phase NA 1

Status

Terminated 2Completed 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 3CNS 2Myeloid 1Lymphoid 1Head & Neck 1Genitourinary 1Breast 1

Conditions

Brain Neoplasms 4Sarcoma 3Neoplasms 3Recurrence 2Ovarian Neoplasms 2Neoplasm Metastasis 2Nasopharyngeal Carcinoma 2Medulloblastoma 2Glioblastoma 2Central Nervous System Neoplasms 2Breast Neoplasms 2Astrocytoma 2Urologic Neoplasms 1Thyroid Neoplasms 1Spinal Cord Neoplasms 1Solid Tumors 1Solid Tumor Malignancies 1Soft Tissue Neoplasms 1Pharyngeal Neoplasms 1Osteosarcoma 1Optic Nerve Glioma 1Neurofibromatosis 2 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroectodermal Tumors, Primitive 1Neuroectodermal Tumors 1Neuroblastoma 1Neoplasms, Mesothelial 1Myelodysplastic Syndromes 1Multiple Acyl Coenzyme A Dehydrogenase Deficiency 1Mouth Neoplasms 1

Interventions

Doxorubicin 27Cyclophosphamide 26Radiotherapy 16Gemcitabine 16Filgrastim 11pembrolizumab 10pazopanib 10Radiation 9Docetaxel 9Cisplatin 9fludarabine 7Trabectedin 7Ipilimumab 7Ifosfamide 7Granulocyte Colony-Stimulating Factor 7Etoposide 7Carboplatin 7Busulfan 7Bevacizumab 7olaratumab 6Temozolomide 6Peripheral Blood Stem Cell Transplantation 6Nivolumab 6Mesna 6Melphalan 6selinexor 5Leucovorin 5Irinotecan 5Celecoxib 5Bortezomib 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × Sarcoma × Valproic Acid × Clear all
NCT01552434 2026-05-15

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

M.D. Anderson Cancer Center

Phase 1 Terminated
154 enrolled
BreastCNSGenitourinaryHead & NeckLymphoidMyeloidSarcoma

Breast Neoplasms, Carcinoma, Transitional Cell, Endocrine Gland Neoplasms, Castleman Disease, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms, Pharyngeal Neoplasms, Recurrence, Sarcoma, Soft Tissue Neoplasms, Thyroid Neoplasms, Urologic Neoplasms, Neurofibromatosis 2, Lymphangioleiomyomatosis, Neoplasms, Mesothelial, Erdheim-Chester Disease

NCT01106872 2018-08-10

Bevacizumab, Chemotherapy and Valproic Acid in Advanced Sarcomas

University of Iowa

Phase 1 Completed
47 enrolled
Sarcoma

Sarcoma

NCT01204450 2016-12-23

Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft Tissue Sarcoma

UNC Lineberger Comprehensive Cancer Center

Phase 1 Terminated
7 enrolled
CNSSarcoma

Neuroblastoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral

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