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Phase

Phase 2 18Phase 3 10Phase NA 3Phase 1 3Phase 1/2 2Phase EARLY_PHASE1 1

Status

Suspended 1Recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 2

Conditions

Lymphoma, Large B-Cell, Diffuse 23Precursor Cell Lymphoblastic Leukemia-Lymphoma 16Lymphoma 14Lymphoma, Non-Hodgkin 10Lymphoma, Follicular 8Lymphoma, B-Cell 8Lymphoma, Mantle-Cell 7Burkitt Lymphoma 7Rhabdomyosarcoma 6Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 6Recurrence 5Leukemia 5Immunoblastic Lymphadenopathy 5Lymphoma, T-Cell, Peripheral 4Lymphoma, Large-Cell, Anaplastic 4Leukemia, Lymphocytic, Chronic, B-Cell 4Sarcoma, Ewing 3Lymphoma, Primary Effusion 3Sarcoma 2Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 2Plasmablastic Lymphoma 2Osteosarcoma 2Neuroblastoma 2Neoplasms 2Myelodysplastic Syndromes 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, T-Cell 2Lymphoma, B-Cell, Marginal Zone 2Hodgkin Disease 2Enteropathy-Associated T-Cell Lymphoma 2

Interventions

Gemcitabine 15pembrolizumab 13Doxorubicin 13Radiotherapy 12Docetaxel 9Nivolumab 8Filgrastim 7Cyclophosphamide 7pazopanib 6Ifosfamide 6130-nm albumin-bound paclitaxel 5Temozolomide 4Irinotecan 4Ipilimumab 4Imatinib Mesylate 4Albumin-Bound Paclitaxel 4talimogene laherparepvec 3surufatinib 3pegfilgrastim 3eribulin 3atezolizumab 3Vinorelbine 3Sirolimus 3Peripheral Blood Stem Cell Transplantation 3PM 01183 3Drug Therapy 3Cisplatin 3toripalimab 2spartalizumab 2selinexor 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1/2 × Sarcoma × Vincristine × Clear all
NCT04890093 2026-03-16

Vincristine and Temozolomide in Combination With PEN-866 for Adolescents and Young Adults With Relapsed or Refractory Solid Tumors

National Institutes of Health Clinical Center (CC)

Phase 1/2 Suspended
64 enrolled
Sarcoma

Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing

NCT06709495 2026-02-19

Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

Dana-Farber Cancer Institute

Phase 1/2 Recruiting
63 enrolled
Sarcoma

Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Desmoplastic Small Round Cell Tumor

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