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Phase

Phase 2 2Phase 1/2 2Phase 1 1

Status

Completed 5

Sponsor Class

OTHER 3NIH 2

Study Type

Interventional 5

Sponsor

Cancer Type

Sarcoma 5Lymphoid 1Genitourinary 1CNS 1

Conditions

Leukemia, Myeloid, Acute 19Lymphoma 17Lymphoma, Large B-Cell, Diffuse 15Precursor Cell Lymphoblastic Leukemia-Lymphoma 14Lymphoma, Non-Hodgkin 14Hodgkin Disease 13Multiple Myeloma 12Lymphoma, Mantle-Cell 12Lymphoma, Follicular 12Carcinoma, Non-Small-Cell Lung 11Breast Neoplasms 11Leukemia, Lymphocytic, Chronic, B-Cell 9Glioblastoma 9Lymphoma, B-Cell, Marginal Zone 8Burkitt Lymphoma 8Brain Neoplasms 8Sezary Syndrome 7Neoplasms 7Lymphoma, T-Cell, Cutaneous 7Leukemia 7Congenital Abnormalities 7Unspecified Adult Solid Tumor, Protocol Specific 6Recurrence 6Neuroblastoma 6Mycosis Fungoides 6Lymphoma, Large-Cell, Immunoblastic 6Lymphoma, Large-Cell, Anaplastic 6Breast Neoplasms, Male 6Sarcoma 5Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 5

Interventions

Doxorubicin 80Ifosfamide 54Radiotherapy 43Filgrastim 41Gemcitabine 38Cyclophosphamide 34Etoposide 26Vincristine 24Cisplatin 24Docetaxel 23pazopanib 21Trabectedin 19Carboplatin 17pembrolizumab 15Peripheral Blood Stem Cell Transplantation 14eribulin 12Mesna 12Melphalan 12Sorafenib 11Sirolimus 11Irinotecan 11Granulocyte Colony-Stimulating Factor 11Bevacizumab 11Topotecan 10Paclitaxel 10Imatinib Mesylate 10Chemotherapy, Adjuvant 10pegfilgrastim 9Temozolomide 9Surgical Procedures, Operative 9

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Completed × Sarcoma × Vorinostat × Clear all
NCT01879085 2022-09-21

GemTax

University of Pittsburgh

Phase 1/2 Completed
37 enrolled 17 charts
Sarcoma

Neoplasm Metastasis, Sarcoma

NCT01294670 2021-11-18

Clinical Study of Vorinostat in Combination With Etoposide in Pediatric Patients < 21 Years at Diagnosis With Refractory Solid Tumors

Memorial Sloan Kettering Cancer Center

Phase 1/2 Completed
27 enrolled 11 charts
Sarcoma

Sarcoma

NCT00918489 2018-10-17

SAHA-I

Heidelberg University

Phase 2 Completed
40 enrolled
Sarcoma

Neoplasm Metastasis, Sarcoma

NCT01132911 2017-07-02

A Phase I Study of Vorinostat and Bortezomib in Children With Refractory of Recurrent Solid Tumors, Including CNS Tumors and Lymphomas

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
5 enrolled
CNSGenitourinaryLymphoidSarcoma

Lymphoma, Neoplasms, Wilms Tumor, Neuroblastoma, Sarcoma

NCT00937495 2014-05-14

Vorinostat and Bortezomib in Treating Patients With Advanced Soft Tissue Sarcoma

National Cancer Institute (NCI)

Phase 2 Completed
16 enrolled 6 charts
Sarcoma

Sarcoma

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