Announcements Trials
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Phase

Phase 1 3

Status

Completed 3Unknown 2Recruiting 2Withdrawn 1Available 1

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 3Gynecologic 1

Conditions

Leukemia, Myeloid, Acute 12Multiple Myeloma 11Recurrence 8Lymphoma, Large B-Cell, Diffuse 4Sarcoma 3Neoplasms 3Lymphoma, Non-Hodgkin 3Endometrial Neoplasms 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Ovarian Neoplasms 2Neoplasms, Plasma Cell 2Myelodysplastic Syndromes 2Melanoma 2Lymphoma, T-Cell, Peripheral 2Lymphoma, B-Cell 2Lymphoma 2Leukemia, Lymphocytic, Chronic, B-Cell 2Leukemia 2Congenital Abnormalities 2Colorectal Neoplasms 2Waldenstrom Macroglobulinemia 1Uterine Neoplasms 1Uterine Diseases 1Uterine Cervical Neoplasms 1Triple Negative Breast Neoplasms 1Solid Tumors 1Sarcoma, Endometrial Stromal 1Salivary Gland Neoplasms 1Pancreatic Neoplasms 1Neurofibrosarcoma 1

Interventions

Doxorubicin 80Ifosfamide 54Radiotherapy 43Filgrastim 41Gemcitabine 38Cyclophosphamide 34Etoposide 26Vincristine 24Cisplatin 24Docetaxel 23pazopanib 21Trabectedin 19Carboplatin 17pembrolizumab 15Peripheral Blood Stem Cell Transplantation 14eribulin 12Mesna 12Melphalan 12Sorafenib 11Sirolimus 11Irinotecan 11Granulocyte Colony-Stimulating Factor 11Bevacizumab 11Topotecan 10Paclitaxel 10Imatinib Mesylate 10Chemotherapy, Adjuvant 10pegfilgrastim 9Temozolomide 9Surgical Procedures, Operative 9

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Completed × Sarcoma × selinexor × Clear all
NCT04811196 2025-05-29

A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients

University Health Network, Toronto

Phase 1 Completed
56 enrolled
GynecologicSarcoma

Leiomyosarcoma, Sarcoma, Sarcoma, Endometrial Stromal, Neurofibrosarcoma

NCT01896505 2024-01-08

A Phase I Trial to Assess the Effects of Food and Formulation on PK of KPT-330 in Patients With Sarcoma

Karyopharm Therapeutics Inc

Phase 1 Completed
54 enrolled 28 charts
Sarcoma

Bone Neoplasms, Sarcoma

NCT03042819 2021-12-09

Study of Selinexor and Doxorubicin in Advanced Soft Tissue Sarcomas

University Health Network, Toronto

Phase 1 Completed
25 enrolled
Sarcoma

Sarcoma

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