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Phase

Phase EARLY_PHASE1 1Phase 3 1

Status

Terminated 1Completed 1

Sponsor Class

OTHER 1NETWORK 1

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 2Gynecologic 2Gastrointestinal 2Thoracic 1Other solid neoplasm 1Genitourinary 1CNS 1

Conditions

Mesothelioma, Malignant 5Hepatoblastoma 5Ototoxicity 4Medulloblastoma 4Central Nervous System Neoplasms 4Peritoneal Neoplasms 3Ovarian Neoplasms 3Hearing Loss 3Gastrointestinal Neoplasms 3Drug-Related Side Effects and Adverse Reactions 3Testicular Neoplasms 2Stomach Neoplasms 2Sarcoma 2Oligodendroglioma 2Neoplasms, Germ Cell and Embryonal 2Liver Neoplasms 2Glioma 2Brain Neoplasms 2Astrocytoma 2Adrenocortical Carcinoma 2Thrombocytopenia 1Teratoma 1Seminoma 1Rhabdomyosarcoma 1Rectal Neoplasms 1Pelvic Neoplasms 1Ovarian Germ Cell Cancer 1Osteosarcoma 1Oropharyngeal Neoplasms 1Optic Nerve Glioma 1

Interventions

Doxorubicin 142Ifosfamide 85Radiotherapy 82Cyclophosphamide 72Gemcitabine 63Filgrastim 54pembrolizumab 43pazopanib 40Etoposide 39Docetaxel 39Vincristine 37Trabectedin 37Cisplatin 35Nivolumab 32Magnetic Resonance Spectroscopy 26Irinotecan 26Carboplatin 25Temozolomide 23Surgical Procedures, Operative 23Radiation 22Ipilimumab 22Bevacizumab 20Blood Specimen Collection 19Granulocyte Colony-Stimulating Factor 18Biopsy 18eribulin 17Sirolimus 17Mesna 17Melphalan 17Dactinomycin 17

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Sarcoma × sodium thiosulfate × Clear all
NCT04213794 2025-02-20

TOASTIT

Mayo Clinic

Phase EARLY_PHASE1 Terminated
2 enrolled
GastrointestinalGynecologicOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Colonic Neoplasms, Fallopian Tube Neoplasms, Liposarcoma, Ovarian Neoplasms, Pelvic Neoplasms, Rectal Neoplasms, Rhabdomyosarcoma, Sarcoma, Stomach Neoplasms, Desmoplastic Small Round Cell Tumor

NCT00716976 2023-11-09

Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

Children's Oncology Group

Phase 3 Completed
131 enrolled 18 charts 1 FDA
CNSGastrointestinalGenitourinaryGynecologicSarcoma

Ovarian Germ Cell Cancer, Ototoxicity, Brain Neoplasms, Liver Neoplasms, Medulloblastoma, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Hepatoblastoma

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