Clinical Trials

52 enrolled

CNSSarcoma

Glioblastoma, Sarcoma

NCT06566092 2026-04-06

Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult Participants

40 enrolled

DermatologicSarcoma

Melanoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing

NCT03478462 2026-03-18

CLOVER-2

CNSGenitourinaryLymphoidSarcoma

30 enrolled

Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioblastoma, Glioma, Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT03715933 2026-03-18

Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

321 enrolled

Sarcoma, Sarcoma, Ewing

NCT07156565 2026-03-17

ATLAS

30 enrolled

Recurrence, Sarcoma

NCT07261631 2026-03-13

Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors

BreastGastrointestinalSarcomaThoracic

180 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Sarcoma, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT07374848 2026-03-05

Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors

180 enrolled

NCT06910657 2026-03-02

IDOV-Immune for Advanced Solid Tumors

BreastDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

78 enrolled

Adrenal Gland Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Vaccinia, Colorectal Neoplasms

NCT04619056 2026-02-19

First-in-man Clinical Trial of CEB-01 PLGA Membrane in Recurrent or Locally Advanced Retroperitoneal Soft Tissue Sarcoma

21 enrolled

Recurrence, Sarcoma

NCT06242470 2026-02-05

A Study of MGC026 in Participants With Advanced Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

250 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Small Cell Lung Carcinoma, Prostatic Neoplasms, Castration-Resistant

NCT04969835 2026-02-04

A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours

BreastGenitourinaryGynecologicHead & NeckSarcoma

158 enrolled

Breast Neoplasms, Carcinoma, Transitional Cell, Ovarian Neoplasms, Salivary Gland Neoplasms, Sarcoma

NCT06771219 2026-01-23

SLV-154 Treatment of Metastatic Solid Tumors

GynecologicHead & NeckSarcoma

70 enrolled

Neoplasm Metastasis, Ovarian Neoplasms, Sarcoma, Thyroid Neoplasms, Endometrial Neoplasms

NCT05238883 2025-11-21

A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

72 enrolled

Testicular Germ Cell Tumor, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Melanoma, Mesothelioma, Sarcoma, Stomach Neoplasms

NCT05229601 2025-10-22

A Study of HFB301001 in Adult Patients With Advanced Solid Tumors

DermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

31 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Melanoma, Sarcoma

NCT06336148 2025-10-15

A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

10 enrolled

Bile Duct Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Melanoma, Mesothelioma, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT06674538 2025-09-22

Clinical Trial to Treat Stage IV Cancer Patients

Phase 1 Enrolling by invitation

12 enrolled

Neoplasms, Sarcoma

NCT05492682 2025-09-05

START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer

BreastDermatologicGastrointestinalSarcomaThoracic

15 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma, Sarcoma, Osteosarcoma, Sarcoma, Synovial, Colorectal Neoplasms, Liposarcoma, Myxoid, Triple Negative Breast Neoplasms

NCT06789172 2025-09-05

INVOKE

GastrointestinalHead & NeckSarcomaThoracic

166 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Liposarcoma, Sarcoma, Colorectal Neoplasms, Dermatofibrosarcoma, Histiocytoma, Malignant Fibrous, Solitary Fibrous Tumors

NCT06942143 2025-09-03

An Open-label, Phase I Clinical Trial of Super1 TCR-T in NY-ESO-1-positive Patients With Advanced Solid Tumors

DermatologicSarcomaThoracic

15 enrolled

Lung Neoplasms, Melanoma, Sarcoma

NCT05114668 2025-09-02

Safety, Tolerability, and Pharmacokinetics of EVT801 in Patients With Advanced Solid Tumours

32 enrolled

GenitourinarySarcoma

Carcinoma, Renal Cell, Neoplasm Metastasis, Neoplasms, Sarcoma

NCT02784795 2025-08-21

A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors

BreastGastrointestinalSarcoma

94 enrolled 28 charts

Breast Neoplasms, Colonic Neoplasms, Sarcoma, Cholangiocarcinoma

NCT05858710 2025-07-28

Study of DPPG2-TSL-DOX Combined With Hyperthermia in Soft Tissue Sarcoma

8 enrolled

NCT06644755 2025-07-24

First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors

Phase 1 Not yet recruiting

150 enrolled

GenitourinarySarcoma

Urinary Bladder Neoplasms, Sarcoma, Sarcoma, Synovial, Liposarcoma, Myxoid

NCT07052383 2025-07-04

Safety and Efficacy of DIT309 in Advanced Bone and Soft Tissue Sarcomas

15 enrolled

Sarcoma, Osteosarcoma

NCT05432193 2025-06-25

FAPi Radioligand OpeN-Label, Phase 1 Study to Evaluate Safety, Tolerability and DosImetry of [Lu-177]-PNT6555; A Dose Escalation Study for TReatment of Patients With Select Solid Tumors (FRONTIER)

DermatologicGastrointestinalHead & NeckSarcoma

20 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Neoplasms, Melanoma, Sarcoma, Colorectal Neoplasms, Cholangiocarcinoma

NCT05389462 2025-05-22

A Study of Mipasetamab Uzoptirine (ADCT-601) in Participants With Solid Tumors

128 enrolled

GastrointestinalSarcoma

Pancreatic Neoplasms, Sarcoma

NCT04553692 2025-03-28

Phase 1a/1b Study of Aplitabart (IGM-8444) Alone or in Combination in Participants with Relapsed, Refractory, or Newly Diagnosed Cancers

GastrointestinalLymphoidOther hematologic neoplasmSarcoma

272 enrolled

Chondrosarcoma, Lymphoma, Non-Hodgkin, Neoplasm Metastasis, Sarcoma, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute

NCT06132503 2025-03-17

Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors

110 enrolled

LymphoidSarcoma

Lymphoma, Neoplasms, Recurrence, Sarcoma

NCT04965753 2025-03-04

FHD-609 in Subjects With Advanced Synovial Sarcoma or Advanced SMARCB1-Loss Tumors

55 enrolled

Sarcoma, Sarcoma, Synovial, Rhabdoid Tumor

NCT04537715 2025-02-19

Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels

LymphoidOther hematologic neoplasmOther solid neoplasmSarcomaThoracic

42 enrolled 39 charts

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mesothelioma, Sarcoma, Sarcoma, Synovial, Lymphoma, Large B-Cell, Diffuse, Rhabdoid Tumor, Hematologic Neoplasms

NCT05100628 2025-01-06

A Study of NOX66 Plus Doxorubicin in Anthracycline-naïve, Adult Patients With Soft Tissue Sarcoma

9 enrolled 10 charts

Phase 1 Not yet recruiting

NCT06748872 2024-12-27

EPITOME-1015-I

55 enrolled

GynecologicSarcoma

Carcinoma, Ovarian Epithelial, Sarcoma, Sarcoma, Synovial, Liposarcoma, Myxoid

NCT03150810 2024-12-20

Study to Assess Safety, Tolerability and Clinical Activity of BGB-290 in Combination With Temozolomide (TMZ) in Participants With Locally Advanced or Metastatic Solid Tumors

BreastGastrointestinalGynecologicHead & NeckSarcomaThoracic

139 enrolled 36 charts

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Head and Neck Neoplasms, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT06537596 2024-12-19

ZOLAR

50 enrolled

NCT05355753 2024-12-17

A Study to Assess the Safety and Tolerability of CFT8634 in Locally Advanced or Metastatic SMARCB1-Perturbed Cancers, Including Synovial Sarcoma and SMARCB1-Null Tumors

49 enrolled

Chondrosarcoma, Extraskeletal Myxoid, Chordoma, Sarcoma, Sarcoma, Synovial

NCT03474640 2024-11-22

Safety, Tolerability and Pharmacokinetics of an Anti-PD-1 Monoclonal Antibody in Subjects With Advanced Malignancies

GastrointestinalHead & NeckSarcoma

184 enrolled 20 charts

Nasopharyngeal Carcinoma, Chondrosarcoma, Esophageal Neoplasms, Carcinoma, Hepatocellular, Sarcoma, Stomach Neoplasms

NCT06699576 2024-11-21

ARTEMIS-103: Phase 1b Study of HS-20093 Combinations in Patients with Bone and Soft Tissue Sarcoma.

Phase 1 Not yet recruiting

448 enrolled

Sarcoma, Osteosarcoma

NCT03960060 2024-10-28

CAR

GastrointestinalGenitourinarySarcoma

9 enrolled

Urinary Bladder Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms

NCT04511871 2024-10-28

A Phase I Trial of CCT303-406 in Patients With Relapsed or Refractory HER2 Positive Solid Tumors

BreastGastrointestinalGynecologicSarcoma

12 enrolled

Breast Neoplasms, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms

NCT05128786 2024-10-28

CCT301-38 CAR-T in Patients With Relapsed or Refractory AXL Positive Sarcomas

9 enrolled

NCT03126591 2024-10-23

A Study of Olaratumab (LY3012207) Plus Pembrolizumab in Participants With Advanced or Metastatic Soft Tissue Sarcoma

41 enrolled 19 charts

NCT05130255 2024-10-02

GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2

60 enrolled

DermatologicSarcoma

Melanoma, Sarcoma

NCT03604783 2024-09-19

Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors

74 enrolled

Liposarcoma, Neoplasm Metastasis, Neoplasms, Sarcoma, Sarcoma, Ewing, Sarcoma, Synovial

NCT03752398 2024-07-05

DUET-3

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

198 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Melanoma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Histiocytoma, Malignant Fibrous, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT05538572 2024-07-01

A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors

BreastCNSGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

22 enrolled

Squamous Cell Carcinoma of Head and Neck, Mesothelioma, Malignant, Breast Neoplasms, Glioblastoma, Sarcoma, Endometrial Neoplasms

NCT05578820 2024-07-01

Safety, Tolerability and Pharmacokinetics Investigation of Stimotimagene Copolymerplasmid

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcoma

21 enrolled

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Melanoma, Penile Neoplasms, Sarcoma, Vulvar Neoplasms

NCT05043649 2024-05-16

Camsirubicin + Pegfilgrastim to Determine MTD in ASTS

14 enrolled

NCT05061537 2024-04-12

Study of PF-07263689 in Participants With Selected Advanced Solid Tumors