Clinical Trials

50 enrolled

NCT07602049 2026-05-22

Cryoablation Plus Camrelizumab for Advanced Soft Tissue Sarcoma

57 enrolled

Sarcoma, Osteosarcoma

NCT06503146 2026-05-19

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

CNSEndocrineGastrointestinalGenitourinaryGynecologicOther solid neoplasmSarcomaThoracic

320 enrolled

Urinary Bladder Neoplasms, Carcinoma, Hepatocellular, Mesothelioma, Ovarian Neoplasms, Paraganglioma, Pheochromocytoma, Sarcoma, Stomach Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma

NCT07089992 2026-05-14

A Study of Pembrolizumab in People With Ultra-Rare Sarcomas

32 enrolled

Liposarcoma, Sarcoma, Perivascular Epithelioid Cell Neoplasms

NCT06760819 2026-05-07

panSOHO

BreastGastrointestinalGenitourinaryGynecologicSarcoma

111 enrolled

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors

NCT04605770 2026-04-30

ALBATROSS

164 enrolled

NCT07243626 2026-04-24

Efficacy and Safety of Envafolimab Plus Doxorubicin and Ifosfamide for Advanced Soft Tissue Sarcoma

25 enrolled

NCT04332874 2026-04-23

A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg

Sarcoma, Dermatofibrosarcoma, Sarcoma, Alveolar Soft Part, Histiocytoma, Malignant Fibrous

NCT07283731 2026-04-17

Phase 2 Trial of Zanzalintinib and Pembrolizumab in Select Subtypes of Advanced/Metastatic Soft-tissue Sarcoma

20 enrolled

Neoplasm Metastasis, Sarcoma

NCT06638931 2026-04-15

ANTARES

BreastCNSEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther solid neoplasmSarcomaThoracic

28 enrolled

Urachal adenocarcinoma, Urachal cancer, Fibrolamellar hepatocellular carcinoma, Secretory breast carcinoma, Carcinoma, Ovarian Epithelial, Adrenal Gland Neoplasms, Anus Neoplasms, Biliary Tract Neoplasms, Carcinosarcoma, Carcinoma, Adenoid Cystic, Fallopian Tube Neoplasms, Fibrosarcoma, Gallbladder Neoplasms, Granulosa Cell Tumor, Hemangiosarcoma, Leiomyosarcoma, Mesothelioma, Neuroblastoma, Parathyroid Neoplasms, Penile Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Thyroid Neoplasms, Trophoblastic Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Hepatoblastoma, Endodermal Sinus Tumor, Neuroectodermal Tumors, Primitive, Cholangiocarcinoma, Sertoli-Leydig Cell Tumor, Neurofibrosarcoma, Hemangioblastoma, Neuroendocrine Tumors

NCT06087861 2026-04-13

5-Day Preoperative Radiation for Soft Tissue Sarcoma

75 enrolled

NCT05926700 2026-04-08

Efficacy and Safety of Cadonilimab Plus Anlotinib in Advanced STS That Failed the Previous First-line Standard Treatment

27 enrolled

NCT06445166 2026-04-06

Propranolol for the Treatment of Kaposi Sarcoma in Adults

25 enrolled

Sarcoma, Sarcoma, Kaposi

NCT07032285 2026-04-06

A Clinical Study to Investigate the Efficacy of Intratumoral Tigilanol Tiglate in Soft Tissue Sarcoma

40 enrolled

Neoplasm Metastasis, Sarcoma

NCT05672108 2026-03-05

Phase II Trial of Lung Chemoemobolization

GastrointestinalSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Mediastinal Neoplasms, Pleural Neoplasms, Sarcoma

NCT07291297 2026-03-05

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

50 enrolled

NCT06815666 2026-03-04

BAL Fluid Biomarkers in Sarcoma

70 enrolled

NCT07447050 2026-03-03

Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

BreastGastrointestinalGynecologicHead & NeckSarcomaThoracic

24 enrolled

Breast Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms, Urogenital Neoplasms, Colorectal Neoplasms

NCT04771520 2026-03-02

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

DermatologicGastrointestinalSarcomaThoracic

50 enrolled

Lung Neoplasms, Melanoma, Neoplasm Metastasis, Sarcoma, Colorectal Neoplasms

NCT04719156 2026-02-20

ICGTM

110 enrolled

NCT07125183 2026-02-05

Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

20 enrolled

Leiomyosarcoma, Sarcoma

NCT05109494 2026-01-28

Hypofractionated vs Conventional Fractionated RT in Soft Tissue Sarcomas

NCT07169344 2026-01-28

PROSARC-1

110 enrolled

Leiomyosarcoma, Liposarcoma, Sarcoma, Sarcoma, Synovial, Dermatofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT07173972 2026-01-28

PROSARC-2

40 enrolled

Leiomyosarcoma, Liposarcoma, Sarcoma, Sarcoma, Synovial, Dermatofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT07359053 2026-01-22

MAGNATE-S

46 enrolled

NCT06849986 2026-01-08

TAIS

45 enrolled

Fibrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Sarcoma, Neurofibrosarcoma, Desmoplastic Small Round Cell Tumor

NCT06835049 2025-12-30

TNT-HYPE

24 enrolled

Hyperthermia, Sarcoma

NCT06942442 2025-12-26

A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma

47 enrolled

Sarcoma, Sarcoma, Clear Cell

NCT07192068 2025-12-19

AcSé HER2

GastrointestinalHead & NeckSarcomaThoracic

105 enrolled

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Sarcoma, Colorectal Neoplasms

NCT05167994 2025-12-11

SPARE-01

NCT06333314 2025-12-02

Pan-MSI-ACSE

120 enrolled

EndocrineSarcoma

Neoplasm Metastasis, Neoplasms, Sarcoma, Adrenocortical Carcinoma, Carcinoma, Neuroendocrine

NCT05182164 2025-10-07

PEMBROCABOSARC

119 enrolled

Sarcoma, Sarcoma, Ewing, Osteosarcoma, Histiocytoma, Malignant Fibrous

NCT06528769 2025-09-30

Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma

16 enrolled

Leiomyosarcoma, Sarcoma

NCT04273061 2025-09-22

CAPTIV-8

BreastDermatologicGastrointestinalHead & NeckSarcomaThoracic

200 enrolled

Breast Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Neoplasms, Unknown Primary, Sarcoma, Skin Neoplasms, Urogenital Neoplasms

NCT04515459 2025-09-15

EPOP-SARCOMA

53 enrolled

Bone Neoplasms, Sarcoma

NCT07014137 2025-09-11

A Trial of ABSK043, an Oral PD-L1 Inhibitor, in Patients With Angiogenic Sarcomas

20 enrolled

NCT06683846 2025-08-24

Ivonescimab in the Treatment of Multiple Advanced Tumors

CNSDermatologicEndocrineGenitourinarySarcoma

400 enrolled

Urachal cancer, Carcinoma, Carcinoma, Basal Cell, Carcinoma, Transitional Cell, Kidney Neoplasms, Paget Disease, Extramammary, Paraganglioma, Penile Neoplasms, Pheochromocytoma, Prostatic Neoplasms, Rhabdomyosarcoma, Sarcoma, Angiomyolipoma, Carcinoma, Neuroendocrine, Perivascular Epithelioid Cell Neoplasms

NCT04776525 2025-08-14

Sequential Neoadjuvant Chemotherapy in Soft Tissue Sarcoma

49 enrolled

NCT04874311 2025-08-13

TRUST

80 enrolled

Tertiary Lymphoid Structures, Neoplasm Metastasis, Sarcoma

NCT05135975 2025-08-12

A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors

86 enrolled

CNSGenitourinarySarcoma

Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT06277154 2025-07-24

MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma

148 enrolled

GynecologicSarcoma

Fibrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Sarcoma, Sarcoma, Synovial, Sarcoma, Endometrial Stromal, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous, Desmoplastic Small Round Cell Tumor

NCT04040205 2025-07-20

Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

Other solid neoplasmSarcoma

44 enrolled

Chondrosarcoma, Retinoblastoma, Sarcoma, Osteosarcoma

NCT05679921 2025-07-16

Pazopanib With or Without Pembrolizumab for Metastatic Soft Tissue Sarcoma

116 enrolled

NCT03935893 2025-07-10

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers