Clinical Trials

65 enrolled

NCT03474094 2026-02-10

RT-Immune

62 enrolled

Phase 1/2 Active not recruiting

NCT05180695 2026-02-10

AMPHISARC

47 enrolled

NCT03628209 2026-02-05

Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma

21 enrolled

Sarcoma, Osteosarcoma

NCT04917042 2026-02-04

Tazemetostat in Malignant Peripheral Nerve Sheath Tumors

10 enrolled 12 charts

Inhibition, Psychological, Sarcoma, Nerve Sheath Neoplasms, Neurofibrosarcoma

NCT03077178 2026-01-30

Melanoma, Sarcoma

NCT02432963 2026-01-28

Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy

BreastDermatologicGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

11 enrolled

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Carcinoma, Hepatocellular, Melanoma, Pancreatic Neoplasms, Rectal Neoplasms, Sarcoma, Triple Negative Breast Neoplasms

NCT00902044 2026-01-26

HEROS

36 enrolled

NCT04425967 2026-01-20

SCOPES

168 enrolled

Phase 1/2 Active not recruiting

NCT00508443 2026-01-15

Evaluation of a Novel CT-On-Rails or Trilogy Stereotactic Spine Radiotherapy System (SSRS)

150 enrolled

BreastDermatologicGastrointestinalLymphoidSarcomaThoracic

Urogenital Diseases, Breast Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Lymphoma, Melanoma, Neoplasms, Sarcoma, Spinal Diseases, Spinal Neoplasms

NCT00582647 2026-01-15

Collection of Tissue & Blood From Patients w/ Benign & Malignant Tumors of the Soft Tissue & Gastrointestinal Tract

Active not recruiting

6,000 enrolled

DermatologicGastrointestinalSarcoma

Bile Duct Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Melanoma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms

NCT06660810 2026-01-15

Neoadjuvant Intralesional Injection of Talimogene Laherparepvec

2 enrolled

NCT04616248 2026-01-07

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

BreastDermatologicSarcoma

14 enrolled

Bone Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Melanoma, Sarcoma, Osteosarcoma, Carcinoma, Merkel Cell

NCT04200443 2026-01-05

Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue Sarcoma

72 enrolled

Leiomyosarcoma, Sarcoma

NCT05075993 2025-12-26

Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors

DermatologicGastrointestinalGynecologicSarcoma

352 enrolled

Uveal Melanoma, Carcinoma, Hepatocellular, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms

NCT04416568 2025-12-17

Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers

45 enrolled

Chordoma, Sarcoma, Rhabdoid Tumor

NCT05776667 2025-12-09

Feasibility Trial of Preoperative 5-Day Hypofractionated Radiotherapy for Primary Soft Tissue Sarcoma

16 enrolled

NCT06128863 2025-12-08

EFTISARC-NEO

40 enrolled

NCT02307630 2025-12-04

PET Imaging of Solid Tumors Using 124I-Humanized 3F8: A Pilot Study

7 enrolled

CNSDermatologicSarcoma

Melanoma, Neuroblastoma, Sarcoma

NCT04388839 2025-11-26

Evolutionary Therapy for Rhabdomyosarcoma

12 enrolled

Rhabdomyosarcoma, Sarcoma

NCT03449108 2025-11-21

LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas

BreastEndocrineGynecologicHead & NeckSarcoma

30 enrolled

Bone Neoplasms, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Giant Cell Tumor of Bone, Histiocytoma, Malignant Fibrous, Triple Negative Breast Neoplasms, Thyroid Carcinoma, Anaplastic

NCT03618381 2025-11-20

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

44 enrolled

Carcinoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT04483778 2025-11-20

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

CNSDermatologicGastrointestinalGenitourinaryOther solid neoplasmSarcoma

68 enrolled

Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT04551430 2025-11-12

Cabozantinib Combined With PD-1 and CTLA-4 Inhibition in Metastatic Soft Tissue Sarcoma

105 enrolled

NCT00077285 2025-11-04

Irinotecan and Carboplatin as Upfront Window Therapy in Treating Patients With Newly Diagnosed Intermediate-Risk or High-Risk Rhabdomyosarcoma

65 enrolled

BreastCNSGastrointestinalSarcoma

Malignant mesenchymal tumor, Rhabdomyosarcoma, Sarcoma

NCT00996710 2025-11-04

Genomic Structural Variation in Cancer Susceptibility

Active not recruiting

1,275 enrolled

Breast Neoplasms, Colonic Neoplasms, Neoplasms, Germ Cell and Embryonal, Neuroblastoma, Rectal Neoplasms, Sarcoma

NCT01223248 2025-11-04

Randomized Study Comparing Two Dosing Schedules for Hypofractionated Image-Guided Radiation Therapy

Phase 3 Active not recruiting

220 enrolled

DermatologicGynecologicSarcoma

Melanoma, Ovarian Neoplasms, Sarcoma, Pyloric Stenosis, Hypertrophic

NCT06208748 2025-10-31

SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST

40 enrolled

GastrointestinalSarcoma

Sarcoma, Gastrointestinal Stromal Tumors

NCT03069378 2025-10-29

A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma

41 enrolled 8 charts

GastrointestinalSarcomaThoracic

Neoplasm Metastasis, Sarcoma

NCT04430725 2025-10-22

Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study

Active not recruiting

74 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Sarcoma, Colorectal Neoplasms

NCT05515575 2025-10-20

A Study of Niraparib in People With Soft Tissue Sarcoma Who Have Changes in Their Tumor DNA

8 enrolled

NCT05886634 2025-10-20

A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcoma

16 enrolled

Liposarcoma, Sarcoma

NCT01552434 2025-10-14

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

BreastCNSGenitourinaryHead & NeckLymphoidMyeloidSarcoma

155 enrolled

Breast Neoplasms, Carcinoma, Transitional Cell, Endocrine Gland Neoplasms, Castleman Disease, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms, Pharyngeal Neoplasms, Recurrence, Sarcoma, Soft Tissue Neoplasms, Thyroid Neoplasms, Urologic Neoplasms, Neurofibromatosis 2, Lymphangioleiomyomatosis, Neoplasms, Mesothelial, Erdheim-Chester Disease

NCT04095208 2025-10-02

CONGRATS

67 enrolled

Tertiary Lymphoid Structures, Neoplasm Metastasis, Neoplasms, Sarcoma

NCT03282344 2025-10-01

A Study of NKTR-214 in Combination With Nivolumab in Patients With Metastatic and/or Locally Advanced Sarcoma

88 enrolled

Phase EARLY_PHASE1 Active not recruiting

NCT05488366 2025-09-22

Immunotherapy Combined With Radiotherapy for Metastatic Sarcoma

9 enrolled

NCT05741944 2025-09-09

VALUE_PERSARC

120 enrolled