Announcements Trials
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Phase

Phase 1 2

Status

Completed 2

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Lymphoid 2Other hematologic neoplasm 1Dermatologic 1

Conditions

Sezary Syndrome 2Mycosis Fungoides 2Lymphoma, T-Cell, Cutaneous 2Thyroid Neoplasms 1Skin Neoplasms 1Recurrence 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Pancreatic Neoplasms 1Ovarian Neoplasms 1Neoplasm Metastasis 1Melanoma 1Lymphoma, T-Cell, Peripheral 1Lymphoma, T-Cell 1Lymphoma, Large-Cell, Anaplastic 1Lymphoma 1Lung Neoplasms 1Leukemia-Lymphoma, Adult T-Cell 1Leukemia, Prolymphocytic, T-Cell 1Leukemia, Myeloid, Acute 1Leukemia 1Colonic Neoplasms 1Carcinoma, Renal Cell 1Carcinoma 1Bronchiolitis Obliterans Syndrome 1Breast Neoplasms 1

Interventions

fludarabine phosphate 19Whole-Body Irradiation 15Peripheral Blood Stem Cell Transplantation 15Mycophenolic Acid 15Tacrolimus 12Cyclosporine 11Cyclophosphamide 11Antilymphocyte Serum 11Busulfan 10Rituximab 7Methotrexate 7Etoposide 6Melphalan 5Flow Cytometry 5Radiotherapy 4Panobinostat 4Lenalidomide 4Filgrastim 4Everolimus 4Dexamethasone 4Calcium Dobesilate 4thymoglobulin 3romidepsin 3pembrolizumab 3mogamulizumab 3fludarabine 3Therapeutics 3Sirolimus 3In Situ Hybridization, Fluorescence 3Immunohistochemistry 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Has results × Sezary Syndrome × Interleukin-15 × Clear all
NCT04185220 2023-01-04

Phase I Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for People With Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary Syndrome

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
6 enrolled 16 charts
LymphoidOther hematologic neoplasm

Mycosis Fungoides, Sezary Syndrome, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT03905135 2022-09-13

Interleukin-15 (IL-5) in Combination With Avelumab (Bavencio) in Relapsed/Refractory Mature T-cell Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
8 enrolled 18 charts
DermatologicLymphoid

Mycosis Fungoides, Sezary Syndrome, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic

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