Announcements Trials
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Phase

Phase 1 2

Status

Completed 2

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Lymphoid 2Other hematologic neoplasm 1Dermatologic 1

Conditions

Sezary Syndrome 2Mycosis Fungoides 2Lymphoma, T-Cell, Cutaneous 2Leukemia, Myeloid, Acute 2Squamous Cell Carcinoma of Head and Neck 1Sarcoma 1Recurrence 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Neuroblastoma 1Myelodysplastic Syndromes 1Melanoma 1Lymphoma, T-Cell, Peripheral 1Lymphoma, T-Cell 1Lymphoma, Large-Cell, Anaplastic 1Lymphoma 1Leukemia-Lymphoma, Adult T-Cell 1Leukemia, Prolymphocytic, T-Cell 1Carcinoma, Renal Cell 1Carcinoma, Non-Small-Cell Lung 1Carcinoma 1Brain Neoplasms 1

Interventions

Peripheral Blood Stem Cell Transplantation 28fludarabine phosphate 25Cyclophosphamide 19Cyclosporine 18Whole-Body Irradiation 17Mycophenolic Acid 17Tacrolimus 15Busulfan 13Antilymphocyte Serum 11Methotrexate 10Methylprednisolone 8Filgrastim 8Vorinostat 7Radiotherapy 7Flow Cytometry 7Etoposide 7Bortezomib 6Psychiatric Rehabilitation 5Everolimus 5Dexamethasone 5Bexarotene 5Alemtuzumab 5Transplantation 4Therapeutics 4Polymerase Chain Reaction 4Panobinostat 4Lenalidomide 4Gemcitabine 4Carboplatin 4Calcium Dobesilate 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Sezary Syndrome × Interleukin-15 × Clear all
NCT04185220 2023-01-04

Phase I Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for People With Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary Syndrome

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
6 enrolled 16 charts
LymphoidOther hematologic neoplasm

Mycosis Fungoides, Sezary Syndrome, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT03905135 2022-09-13

Interleukin-15 (IL-5) in Combination With Avelumab (Bavencio) in Relapsed/Refractory Mature T-cell Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
8 enrolled 18 charts
DermatologicLymphoid

Mycosis Fungoides, Sezary Syndrome, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic

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