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Phase

Phase 2 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 17Leukemia 15Precursor Cell Lymphoblastic Leukemia-Lymphoma 14Myelodysplastic Syndromes 12Lymphoma 11Multiple Myeloma 9Leukemia, Myelogenous, Chronic, BCR-ABL Positive 8Lymphoma, Non-Hodgkin 7Leukemia, Lymphocytic, Chronic, B-Cell 6Hematologic Neoplasms 5Hodgkin Disease 4Sarcoma, Ewing 3Rhabdomyosarcoma 3Neuroblastoma 3Neoplasms, Plasma Cell 3Lymphoma, Follicular 3Graft vs Host Disease 3Burkitt Lymphoma 3Brain Neoplasms 3Wilms Tumor 2Waldenstrom Macroglobulinemia 2Testicular Neoplasms 2Sarcoma 2Neuroectodermal Tumors, Primitive, Peripheral 2Neoplasms 2Myeloproliferative Disorders 2Medulloblastoma 2Lymphoma, Large B-Cell, Diffuse 2Lymphoma, B-Cell, Marginal Zone 2Leukemia, Myeloid 2

Interventions

fludarabine phosphate 4Tacrolimus 3Peripheral Blood Stem Cell Transplantation 3Whole-Body Irradiation 2Methotrexate 2Melphalan 2Cyclophosphamide 2treosulfan 1thymoglobulin 1merphos 1fludarabine 1X-Rays 1Thiotepa 1Mycophenolic Acid 1Methylprednisolone Hemisuccinate 1Methylprednisolone 1Busulfan 1Bone Marrow Transplantation 1Antilymphocyte Serum 1Alemtuzumab 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
OTHER × Shwachman-Diamond Syndrome × Bone Marrow Transplantation × Clear all
NCT04965597 2026-03-09

Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

Fred Hutchinson Cancer Center

Phase 2 Completed
40 enrolled
Classical hematology

Congenital amegakaryocytic thrombocytopenia, Bone Marrow Failure Disorders, Shwachman-Diamond Syndrome, Anemia, Hypochromic, Hemoglobinuria, Paroxysmal, Anemia, Diamond-Blackfan

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