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Phase

Phase EARLY_PHASE1 1Phase 3 1

Status

Completed 2Active not recruiting 2Terminated 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Dermatologic 2

Conditions

Melanoma 9Carcinoma, Non-Small-Cell Lung 3Thyroid Neoplasms 2Skin Neoplasms 2Pancreatic Neoplasms 2Ovarian Neoplasms 2Multiple Myeloma 2Lymphoma 2Lung Neoplasms 2Hematologic Neoplasms 2Breast Neoplasms 2Brain Neoplasms 2Uveal Melanoma 1Uterine Neoplasms 1Uterine Cervical Neoplasms 1Urinary Bladder Neoplasms 1Triple Negative Breast Neoplasms 1Thyroid Diseases 1Stomach Neoplasms 1Solid Tumor 1Rectal Neoplasms 1Prostatic Neoplasms 1Neoplasm Metastasis 1Klatskin Tumor 1Glioma 1Gastrointestinal Stromal Tumors 1Gallbladder Neoplasms 1Eye Neoplasms 1Esophageal Neoplasms 1Endometrial Neoplasms 1

Interventions

pembrolizumab 7cemiplimab 6Nivolumab 5avelumab 3encorafenib 2binimetinib 2Radiotherapy 2Ipilimumab 2Immune Checkpoint Inhibitors 2Blood Specimen Collection 2toripalimab 1tislelizumab 1lifileucel 1lenvatinib 1durvalumab 1dostarlimab 1cobimetinib 1atezolizumab 1Vemurafenib 1Surveys and Questionnaires 1Sirolimus 1Radiosurgery 1Prednisone 1Paclitaxel 1Oxaliplatin 1Observation 1Mohs Surgery 1Methylprednisolone Hemisuccinate 1Methylprednisolone 1Magnetic Resonance Spectroscopy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Active not recruiting × Skin Neoplasms × binimetinib × Clear all
NCT04657991 2026-04-07

A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma

Pfizer

Phase 3 Active not recruiting
257 enrolled
Dermatologic

Melanoma, Skin Neoplasms

NCT03543969 2026-02-05

Adaptive BRAF-MEK Inhibitor Therapy for Advanced BRAF Mutant Melanoma

H. Lee Moffitt Cancer Center and Research Institute

Phase EARLY_PHASE1 Active not recruiting
14 enrolled
Dermatologic

Melanoma, Skin Neoplasms

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