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Phase

Phase EARLY_PHASE1 1Phase 3 1

Status

Active not recruiting 2Terminated 1Completed 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Dermatologic 2

Conditions

Melanoma 7Colorectal Neoplasms 5Colonic Neoplasms 5Rectal Neoplasms 4Skin Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Brain Neoplasms 2Thyroid Neoplasms 1Solid Tumor 1Rectal Diseases 1Neoplasms 1Lung Neoplasms 1Intestinal Neoplasms 1Intestinal Diseases 1Gastrointestinal Neoplasms 1Gastrointestinal Diseases 1Disease Progression 1Digestive System Neoplasms 1Digestive System Diseases 1Colonic Diseases 1

Interventions

pembrolizumab 7cemiplimab 6Nivolumab 5avelumab 3encorafenib 2binimetinib 2Radiotherapy 2Ipilimumab 2Immune Checkpoint Inhibitors 2Blood Specimen Collection 2toripalimab 1tislelizumab 1lifileucel 1lenvatinib 1durvalumab 1dostarlimab 1cobimetinib 1atezolizumab 1Vemurafenib 1Surveys and Questionnaires 1Sirolimus 1Radiosurgery 1Prednisone 1Paclitaxel 1Oxaliplatin 1Observation 1Mohs Surgery 1Methylprednisolone Hemisuccinate 1Methylprednisolone 1Magnetic Resonance Spectroscopy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Active not recruiting × Skin Neoplasms × encorafenib × Clear all
NCT04657991 2026-04-07

A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma

Pfizer

Phase 3 Active not recruiting
257 enrolled
Dermatologic

Melanoma, Skin Neoplasms

NCT03543969 2026-02-05

Adaptive BRAF-MEK Inhibitor Therapy for Advanced BRAF Mutant Melanoma

H. Lee Moffitt Cancer Center and Research Institute

Phase EARLY_PHASE1 Active not recruiting
14 enrolled
Dermatologic

Melanoma, Skin Neoplasms

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