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Phase

Phase 1 6Phase 2 5Phase NA 3Phase 3 3Phase 1/2 3Phase 2/3 2Phase EARLY_PHASE1 1

Status

Terminated 2Recruiting 1

Sponsor Class

INDUSTRY 3

Study Type

Interventional 3

Sponsor

Cancer Type

Dermatologic 3Head & Neck 2Thoracic 1Other solid neoplasm 1Gynecologic 1Genitourinary 1Gastrointestinal 1Breast 1

Conditions

Carcinoma, Non-Small-Cell Lung 91Melanoma 74Squamous Cell Carcinoma of Head and Neck 47Neoplasms 44Neoplasm Metastasis 43Lung Neoplasms 37Carcinoma, Renal Cell 36Colorectal Neoplasms 35Breast Neoplasms 34Triple Negative Breast Neoplasms 30Stomach Neoplasms 26Carcinoma, Transitional Cell 26Ovarian Neoplasms 25Head and Neck Neoplasms 24Parkinson Disease 4, Autosomal Dominant Lewy Body 21Esophageal Neoplasms 20Pancreatic Neoplasms 18Uterine Cervical Neoplasms 17Urinary Bladder Neoplasms 16Endometrial Neoplasms 16Small Cell Lung Carcinoma 15Carcinoma, Hepatocellular 15Sarcoma 13Recurrence 12Glioblastoma 12Carcinoma 12Prostatic Neoplasms 11Lymphoma 11Mesothelioma 9Carcinoma, Merkel Cell 9

Interventions

pembrolizumab 3fludarabine 3Cyclophosphamide 3Ipilimumab 2smallpox and monkeypox vaccine modified vaccinia ankara-bavarian nordic 1sargramostim 1reolysin 1poly ICLC 1peginterferon alfa-2a 1osimertinib 1gusacitinib 1fludarabine phosphate 1eprenetapopt 1epacadostat 1dabrafenib 1cobimetinib 1cemiplimab 1Vorinostat 1Temozolomide 1Radiotherapy 1Radiation 1Poly I-C 1Nivolumab 1Monatide (IMS 3015) 1Methods 1MAPRE1 protein, human 1Interleukin-2 1Interleukin-15 1Interleukin-12 1IT-101 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1/2 × Skin Neoplasms × pembrolizumab × Clear all
NCT05086692 2025-07-09

ABILITY-1

Medicenna Therapeutics, Inc.

Phase 1/2 Recruiting
115 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Turcot syndrome, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Mesothelioma, Malignant, Urinary Bladder Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Fallopian Tube Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Skin Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT03684785 2022-04-07

Intratumoral Cavrotolimod Combined With Pembrolizumab or Cemiplimab in Patients With Merkel Cell Carcinoma, Cutaneous Squamous Cell Carcinoma, or Other Advanced Solid Tumors

Exicure, Inc.

Phase 1/2 Terminated
57 enrolled
Dermatologic

Melanoma, Skin Neoplasms, Carcinoma, Merkel Cell

NCT02521870 2021-08-03

SYNERGY-001

Dynavax Technologies Corporation

Phase 1/2 Terminated
241 enrolled 23 charts
DermatologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Melanoma, Skin Neoplasms

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