Clinical Trials

Phase 1/2 Active not recruiting

Skin Neoplasms, Carcinoma, Merkel Cell

NCT07422805 2026-05-27

ctDNA

176 enrolled

Phase NA Not yet recruiting

Melanoma, Skin Neoplasms

NCT07606287 2026-05-26

Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital

4,000 enrolled

BreastCNSDermatologicGastrointestinalHead & Neck

Breast Neoplasms, Endocrine Gland Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Skin Neoplasms, Soft Tissue Neoplasms, Urogenital Neoplasms, Central Nervous System Neoplasms

NCT06489301 2026-05-22

Mechanisms for Laser-Induced Rejuvenation

12 enrolled

Skin Neoplasms

NCT07330323 2026-05-22

CARES

150 enrolled

Skin Neoplasms

NCT05779423 2026-05-19

Cryoablation+Ipilimumab+Nivolumab in Melanoma

37 enrolled

Melanoma, Skin Neoplasms

NCT05574101 2026-05-15

A Study of Radiation Therapy and Cemiplimab for People With Skin Cancer

34 enrolled

Carcinoma, Squamous Cell, Skin Neoplasms

NCT05715255 2026-05-14

Adaptive Symptom Self-Management Immunotherapy Study

BreastDermatologicGastrointestinalThoracic

400 enrolled

Breast Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasms, Rectal Neoplasms, Skin Neoplasms

NCT06673329 2026-05-13

Brodalumab in the Treatment of Immune-Related Adverse Events

Phase 1 Recruiting

11 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Mouth Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thyroid Neoplasms

NCT07455331 2026-05-11

LANCE

Phase 2 Not yet recruiting

60 enrolled

Phase 4 Enrolling by invitation

Carcinoma, Basal Cell, Skin Neoplasms

NCT07575230 2026-05-11

Suzetrigine vs Norco-postoperative Mohs Pain

75 enrolled

Skin Neoplasms

NCT05297734 2026-04-30

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicMyeloidSarcomaThoracic

2,996 enrolled

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Death, Esophageal Neoplasms, Glioblastoma, Lung Diseases, Lung Neoplasms, Melanoma, Myelodysplastic Syndromes, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Sarcoma, Osteosarcoma, Skin Neoplasms, Stomach Neoplasms, Thoracic Neoplasms, Urogenital Neoplasms, Disease Progression, Small Cell Lung Carcinoma

NCT04064424 2026-04-20

Cancer Prevention & Online Technologies

Phase NA Withdrawn

Phase 2 Not yet recruiting

Skin Neoplasms

NCT07387198 2026-04-17

NeoMatryx

135 enrolled

Phase NA Not yet recruiting

Skin Neoplasms, Carcinoma, Merkel Cell

NCT07524062 2026-04-13

THERMS

120 enrolled

Postoperative Complications, Skin Neoplasms, Surgical Wound Infection

NCT04869137 2026-04-08

Neoadjuvant Lenvatinib Plus Pembrolizumab in Merkel Cell Carcinoma

26 enrolled 9 charts

Skin Neoplasms, Carcinoma, Merkel Cell

NCT06694571 2026-04-03

STARS

Phase NA Completed

38 enrolled 9 charts

Melanoma, Skin Neoplasms

NCT07510061 2026-04-03

ICARUS

80 enrolled

Phase EARLY_PHASE1 Not yet recruiting

Hyperthermia, Skin Neoplasms, Heat Stress Disorders, Cognitive Dysfunction

NCT07286318 2026-04-02

A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Transplant Recipients

20 enrolled

Carcinoma, Basal Cell, Skin Neoplasms, Keratosis, Actinic

NCT04562129 2026-04-01

IL2 With Ipilimumab Followed by Nivolumab in Stage 3 or 4 Melanoma Patients

29 enrolled

Melanoma, Skin Neoplasms

NCT05070403 2026-04-01

Study of Afatinib in Advanced Cutaneous Squamous Cell Carcinoma

25 enrolled

Phase EARLY_PHASE1 Recruiting

Carcinoma, Squamous Cell, Skin Neoplasms

NCT05651828 2026-04-01

Adaptive Therapy of Vismodegib in Advanced Basal Cell Carcinoma

34 enrolled

Skin Neoplasms

NCT06298734 2026-04-01

High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

40 enrolled

Phase 1 Active not recruiting

Melanoma, Skin Neoplasms

NCT04387084 2026-03-23

Short-term Fasting Prior to PD-1/PD-L1 Inhibitor Therapy for of Advanced or Metastatic Skin Malignancy

10 enrolled

DermatologicGenitourinaryHead & NeckOther solid neoplasmSarcomaThoracic

Skin Neoplasms

NCT03420963 2026-03-20

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Phase 1 Terminated

12 enrolled

Mesothelioma, Malignant, Bone Neoplasms, Endocrine Gland Neoplasms, Melanoma, Mouth Neoplasms, Pharyngeal Neoplasms, Sarcoma, Skin Neoplasms, Thyroid Neoplasms, Urologic Neoplasms

NCT05702398 2026-03-20

Pilot Trial of Supplemental Vitamin A and Nicotinamide

Phase EARLY_PHASE1 Recruiting

30 enrolled

Phase NA Not yet recruiting

Skin Neoplasms

NCT07482956 2026-03-19

BCC-One-Stop-Study

290 enrolled

Carcinoma, Basal Cell, Skin Neoplasms

NCT03071406 2026-03-11

Randomized Study of Nivolumab+Ipilimumab+/- SBRT for Metastatic Merkel Cell Carcinoma

50 enrolled 12 charts

Neoplasm Metastasis, Skin Neoplasms, Carcinoma, Merkel Cell

NCT06981325 2026-03-11

CEMI-first

34 enrolled

Carcinoma, Basal Cell, Skin Neoplasms

NCT06167096 2026-03-05

Effects of Lavender Aromatherapy on Patient Anxiety During Mohs Micrographic Surgery

Phase NA Completed

89 enrolled

Phase 1 Active not recruiting

Skin Neoplasms

NCT02721459 2026-03-02

XL888 + Vemurafenib + Cobimetinib for Unresectable BRAF Mutated Stage III/IV Melanoma

26 enrolled

Melanoma, Skin Neoplasms

NCT07436390 2026-03-02

MAK

Phase NA Completed

132 enrolled

Melanoma, Skin Neoplasms

NCT03716193 2026-02-27

Measurement of the Partial Pressure of Oxygen in Cutaneous Tumors Using Electron Paramagnetic Resonance (EPR) Oximetry

Phase NA Terminated

3 enrolled

Phase 4 Not yet recruiting

Melanoma, Skin Neoplasms

NCT07426484 2026-02-23

Cosibelimab for CSCC in Patients With Kidney Transplant or Hematologic Malignancy

80 enrolled

DermatologicLymphoidOther hematologic neoplasmPlasma cell

Lymphoma, Waldenstrom Macroglobulinemia, Skin Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Neoplasms, Plasma Cell

NCT04526730 2026-02-20

Neoadjuvant Immunotherapy With Tavo + Electroporation in Combination With Nivo. in Melanoma Patients

Phase 2 Completed

17 enrolled 11 charts

Melanoma, Skin Neoplasms

NCT07042243 2026-02-20

The Florida ASCENT Study

BreastDermatologicGastrointestinalGenitourinaryOther hematologic neoplasmThoracic

100 enrolled

Breast Neoplasms, Feeding Behavior, Food Preferences, Lung Neoplasms, Melanoma, Neoplasms, Prostatic Neoplasms, Skin Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Malnutrition

NCT07422779 2026-02-20

MAK

100 enrolled

Melanoma, Skin Neoplasms

NCT07404605 2026-02-19

Electrochemotherapy-Induced Changes in Tumor Microenvironment in Cutaneous Melanoma

150 enrolled

Melanoma, Skin Neoplasms

NCT07288073 2026-02-13

TIL Therapy in cSCC and MCC

14 enrolled

Phase EARLY_PHASE1 Active not recruiting

Skin Neoplasms, Carcinoma, Merkel Cell

NCT05358938 2026-02-06

Exercise to Boost Response to Checkpoint Blockade Immunotherapy

22 enrolled

Phase EARLY_PHASE1 Active not recruiting

Melanoma, Motor Activity, Skin Neoplasms, Carcinoma, Merkel Cell

NCT03543969 2026-02-05

Adaptive BRAF-MEK Inhibitor Therapy for Advanced BRAF Mutant Melanoma

14 enrolled

Melanoma, Skin Neoplasms

NCT03944941 2026-02-05

Avelumab With or Without Cetuximab in Treating Patients With Advanced Skin Squamous Cell Cancer

60 enrolled