Announcements Trials
Browse Landscape

Phase

Phase 3 2

Status

Terminated 1Recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Thoracic 2CNS 2Genitourinary 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Brain Neoplasms 5Small Cell Lung Carcinoma 2Neoplasm Metastasis 2Lung Neoplasms 2Neurotoxicity Syndromes 1Melanoma 1Gastrointestinal Neoplasms 1Cognitive Dysfunction 1Central Nervous System Carcinoma 1Carcinoma, Renal Cell 1Carcinoma, Non-Small-Cell Lung 1Breast Neoplasms 1

Interventions

Etoposide 34Carboplatin 31Topotecan 24Cisplatin 21atezolizumab 11PM 01183 8durvalumab 7Irinotecan 7amrubicin 5PE regimen 4AMG 757 4rovalpituzumab tesirine 3pembrolizumab 3Magnetic Resonance Spectroscopy 3Dexamethasone 3tremelimumab 2tislelizumab 2etoposide phosphate 2apatinib 2Vitamin E 2Tiragolumab 2Specimen Handling 2Radiosurgery 2RRx-001 2Paclitaxel 2Memantine 2Injections 2EC regimen 2trilaciclib 1toripalimab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 3 × Small Cell Lung Carcinoma × Memantine × Clear all
NCT04588246 2026-05-20

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

NRG Oncology

Phase 3 Terminated
19 enrolled 19 charts
BreastCNSDermatologicGastrointestinalGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT04804644 2026-05-04

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

NRG Oncology

Phase 3 Recruiting
200 enrolled
CNSThoracic

Brain Neoplasms, Lung Neoplasms, Small Cell Lung Carcinoma

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