Clinical Trials

Phase 2 Not yet recruiting

Small Cell Lung Carcinoma

NCT07465757 2026-03-12

ALISCA-Lung2

50 enrolled

CNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Small Cell Lung Carcinoma

NCT06047379 2026-03-02

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Phase 1/2 Recruiting

134 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Astrocytoma, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioblastoma, Melanoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Central Nervous System Neoplasms, Small Cell Lung Carcinoma

NCT03595059 2025-12-10

A Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid Tumors

168 enrolled

BreastThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Neoplasms, Small Cell Lung Carcinoma

NCT05652686 2025-09-23

A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

Phase 1/2 Recruiting

203 enrolled

EndocrineThoracic

Lung Neoplasms, Carcinoma, Neuroendocrine, Small Cell Lung Carcinoma

NCT05420636 2025-07-30

Iadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NET

Phase 2 Terminated

20 enrolled

EndocrineThoracic

Carcinoma, Neuroendocrine, Small Cell Lung Carcinoma

NCT06954246 2025-06-18

A Study of MHB088C Injection Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

Phase 3 Recruiting

450 enrolled

Small Cell Lung Carcinoma

NCT04314895 2025-05-23

Trial of NanoPac Intratumoral Injection in Lung Cancer

18 enrolled 12 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT05800587 2025-04-04

Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

Phase 2 Recruiting

280 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT03509012 2025-01-14

CLOVER

105 enrolled

Head & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma

NCT00062010 2023-07-07

Interferon Alfa, Isotretinoin, and Paclitaxel in Treating Patients With Recurrent Small Cell Lung Cancer

37 enrolled 8 charts

Lung Neoplasms, Small Cell Lung Carcinoma

NCT04672928 2023-02-27

A Phase Ib/III Clinical Study to Evaluate the Efficacy and Safety of IBI318 in Combination With Paclitaxel Versus Placebo in Combination With Paclitaxel in Patients With Small Cell Lung Cancer Who Have Failed First-line or Above Chemotherapies

20 enrolled

Small Cell Lung Carcinoma

NCT04210037 2022-07-12

Study of APG-1252 Plus Paclitaxel in Patients With Relapsed/Refractory Small Cell Lung Cancer

Phase 1/2 Terminated

28 enrolled

Small Cell Lung Carcinoma

NCT01840579 2021-06-22

MK-3475-011

57 enrolled 60 charts

Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma

NCT02551432 2020-02-10

MISP-MK3475

26 enrolled 9 charts

Small Cell Lung Carcinoma

NCT00617409 2019-11-08

To Immunize Patients With Extensive Stage SCLC Combined With Chemo With or Without All Trans Retinoic Acid

69 enrolled 10 charts

Small Cell Lung Carcinoma

NCT02367352 2019-06-26

Alisertib (MLN8237) in Combination With Weekly Paclitaxel in East Asian Patients With Advanced Solid Tumors

Phase 1 Terminated

9 enrolled 14 charts

GynecologicThoracic

Ovarian Neoplasms, Small Cell Lung Carcinoma

NCT02069158 2019-05-21

IOSI-NDU-001

BreastGynecologicHead & NeckThoracic

17 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms, Small Cell Lung Carcinoma

NCT02038647 2018-12-27

Phase 2 Study of Alisertib (MLN8237) in Combination With Paclitaxel Versus Placebo in Combination With Paclitaxel as Second Line Therapy for Small Cell Lung Cancer (SCLC)

178 enrolled 27 charts

Small Cell Lung Carcinoma

NCT00527735 2018-07-18

Phase II Study for Previously Untreated Subjects With Non Small Cell Lung Cancer (NSCLC) or Small Cell Lung Cancer (SCLC)

334 enrolled 29 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT00454324 2017-07-11

NRR

Phase 2 Terminated

30 enrolled 12 charts

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00003281 2016-07-13

Topotecan and Paclitaxel in Treating Patients With Recurrent or Refractory Small Cell Lung Cancer

84 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00020007 2015-04-29

Paclitaxel and Hyperthermic Perfusion in Treating Patients With Lung Cancer or Lung Metastases That Cannot Be Removed By Surgery

Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT00006374 2014-01-15

Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Phase 2 Withdrawn

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00003284 2014-01-06

High-Dose Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Lung Cancer

Phase 2 Unknown

30 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT00028535 2013-06-04

Interleukin-12, Paclitaxel, and Trastuzumab in Treating Patients With Solid Tumors

BreastGastrointestinalGynecologicThoracic

18 enrolled

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Stomach Neoplasms, Endometrial Neoplasms, Breast Neoplasms, Male, Small Cell Lung Carcinoma

NCT01079481 2013-05-30

Combination Anticancer Therapy of Paclitaxel and Everolimus for Relapsed or Refractory Small Cell Lung Cancer

21 enrolled

Recurrence, Small Cell Lung Carcinoma

NCT00021333 2013-04-17

Paclitaxel and Cisplatin Plus Radiation Therapy Followed by Filgrastim in Treating Patients With Recurrent Head and Neck Cancer or Lung Cancer

29 enrolled

CNSHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Neoplasms, Salivary Gland Neoplasms, Thyroid Neoplasms, Esthesioneuroblastoma, Olfactory, Small Cell Lung Carcinoma

NCT00005032 2013-02-11

Bcl-2 Antisense Oligodeoxynucleotide G3139 and Paclitaxel in Treating Patients With Recurrent Small Cell Lung Cancer

Phase 1/2 Completed

12 enrolled

GenitourinaryOther solid neoplasmThoracic

Lung Neoplasms, Small Cell Lung Carcinoma

NCT01604863 2012-11-01

A Study of HGS1036 in Combination With Chemotherapy in Subjects With Advanced Solid Malignancies

Phase 1 Suspended

54 enrolled

Lung Neoplasms, Mesothelioma, Neoplasms, Prostatic Neoplasms, Small Cell Lung Carcinoma

NCT00003589 2012-03-06

Combination Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer

Phase 3 Completed

450 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT00317200 2011-05-02

A Study of Paclitaxel Plus Bevacizumab in Patients With Chemosensitive Relapsed Small Cell Lung Cancer

34 enrolled

Small Cell Lung Carcinoma

NCT00453167 2010-07-12

Weekly Paclitaxel Plus Gemcitabine as Second-line in Small Cell Lung Cancer

35 enrolled