Announcements Trials
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Phase

Phase 2 2Phase 1/2 2

Status

Unknown 2Active not recruiting 2

Sponsor Class

OTHER 3INDUSTRY 1

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 4Gastrointestinal 1Endocrine 1

Conditions

Ovarian Neoplasms 69Neoplasms 21Breast Neoplasms 21Fallopian Tube Neoplasms 18Prostatic Neoplasms 15Neoplasm Metastasis 9Pancreatic Neoplasms 8Endometrial Neoplasms 8Carcinoma, Ovarian Epithelial 8Glioblastoma 7Triple Negative Breast Neoplasms 6Lung Neoplasms 5Small Cell Lung Carcinoma 4Glioma 4Squamous Cell Carcinoma of Head and Neck 3Recurrence 3Mesothelioma 3Melanoma 3Head and Neck Neoplasms 3Cystadenocarcinoma, Serous 3Cholangiocarcinoma 3Carcinoma 3Uterine Neoplasms 2Uterine Cervical Neoplasms 2Urogenital Neoplasms 2Stomach Neoplasms 2Solid Tumor 2Sarcoma 2Prostatic Neoplasms, Castration-Resistant 2Ovarian Diseases 2

Interventions

Etoposide 155Carboplatin 144Cisplatin 105Topotecan 76durvalumab 52atezolizumab 50Irinotecan 45pembrolizumab 38Paclitaxel 34Nivolumab 33Radiotherapy 31PM 01183 24Drug Therapy 24anlotinib 23Gemcitabine 21apatinib 19Ipilimumab 18Docetaxel 17Temozolomide 16Platinum 16Radiosurgery 15Pemetrexed 14toripalimab 13tislelizumab 13olaparib 13Magnetic Resonance Spectroscopy 13Bevacizumab 13rovalpituzumab tesirine 11amrubicin 11Specimen Handling 11

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Small Cell Lung Carcinoma × niraparib × Clear all
NCT04701307 2026-04-22

Niraparib and Dostarlimab for the Treatment of Small Cell Lung Cancer and Other High-Grade Neuroendocrine Carcinomas

M.D. Anderson Cancer Center

Phase 2 Active not recruiting
48 enrolled
EndocrineThoracic

Lung Neoplasms, Carcinoma, Neuroendocrine, Small Cell Lung Carcinoma

NCT03830918 2026-02-12

Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy

Jonsson Comprehensive Cancer Center

Phase 1/2 Active not recruiting
59 enrolled
Thoracic

Lung Neoplasms, Small Cell Lung Carcinoma

NCT05162196 2022-05-02

The Efficacy and Safety of Radiotherapy Plus Niraparib and Toripalimab in Patients With Recurrent Small Cell Lung Cancer

Wuhan University

Phase 2 Unknown
57 enrolled
Thoracic

Small Cell Lung Carcinoma

NCT03221400 2022-02-17

PEN-866 in Patients With Advanced Solid Malignancies

Tarveda Therapeutics

Phase 1/2 Unknown
340 enrolled
GastrointestinalThoracic

Anus Neoplasms, Carcinoma, Carcinoma, Squamous Cell, Neoplasms, Stomach Neoplasms, Small Cell Lung Carcinoma

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