Announcements Trials
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Phase

Phase 2 3Phase 1/2 1

Status

Completed 3Terminated 1

Sponsor Class

NIH 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 4

Conditions

Small Cell Lung Carcinoma 4Neuroectodermal Tumors, Primitive, Peripheral 4Unspecified Adult Solid Tumor, Protocol Specific 2Sarcoma 2Rhabdomyosarcoma 2Medulloblastoma 2Carcinoma, Ovarian Epithelial 2Wilms Tumor 1Testicular Neoplasms 1Sarcoma, Ewing 1Retinoblastoma 1Recurrence 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Ovarian Neoplasms 1Optic Nerve Glioma 1Neuroblastoma 1Meningeal Carcinomatosis 1Malignant mesenchymal tumor 1Lymphoma, Large B-Cell, Diffuse 1Leukemia, Myelomonocytic, Acute 1Leukemia, Myeloid, Acute 1Leukemia, Monocytic, Acute 1Leukemia, Megakaryoblastic, Acute 1Leukemia, Erythroblastic, Acute 1Familial ependymoma 1Dendritic Cell Sarcoma, Interdigitating 1Congenital Abnormalities 1Burkitt Lymphoma 1Brenner Tumor 1Brain Neoplasms 1

Interventions

Etoposide 154Carboplatin 142Cisplatin 104Topotecan 74durvalumab 48atezolizumab 46Irinotecan 44pembrolizumab 39Paclitaxel 34Nivolumab 33Radiotherapy 29anlotinib 23PM 01183 22Gemcitabine 21Drug Therapy 20apatinib 19Ipilimumab 18Docetaxel 17Temozolomide 16Platinum 16Radiosurgery 15Pemetrexed 14toripalimab 13tislelizumab 13olaparib 13Bevacizumab 13amrubicin 11Magnetic Resonance Spectroscopy 11Cyclophosphamide 11rovalpituzumab tesirine 10

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Interventional × Small Cell Lung Carcinoma × trioctyl phosphine oxide × Clear all
NCT01803269 2020-06-26

Topotecan Hydrochloride or Cyclodextrin-Based Polymer-Camptothecin CRLX101 in Treating Patients With Recurrent Small Cell Lung Cancer

University of Chicago

Phase 2 Terminated
29 enrolled 14 charts
Thoracic

Small Cell Lung Carcinoma

NCT00098956 2018-07-23

7-hydroxystaurosporine and Topotecan Hydrochloride in Treating Patients With Relapsed or Progressed Small Cell Lung Cancer

National Cancer Institute (NCI)

Phase 2 Completed
19 enrolled 9 charts
Thoracic

Small Cell Lung Carcinoma

NCT00828139 2017-08-21

S0802 - Topotecan With or Without Aflibercept in Treating Patients With Extensive-Stage Small Cell Lung Cancer

National Cancer Institute (NCI)

Phase 2 Completed
189 enrolled 15 charts
Thoracic

Small Cell Lung Carcinoma

NCT00521144 2015-05-05

Obatoclax Mesylate and Topotecan Hydrochloride in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer or Advanced Solid Tumors

National Cancer Institute (NCI)

Phase 1/2 Completed
22 enrolled 9 charts
Thoracic

Small Cell Lung Carcinoma

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