Announcements Trials
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Phase

Phase 1 3Phase 1/2 1

Status

Completed 2Terminated 1

Sponsor Class

INDUSTRY 3

Study Type

Interventional 3

Sponsor

Cancer Type

Thoracic 3Breast 2Plasma cell 1Other solid neoplasm 1Other hematologic neoplasm 1Lymphoid 1Head & Neck 1Gynecologic 1Genitourinary 1Gastrointestinal 1Dermatologic 1

Conditions

Leukemia, Myeloid, Acute 95Myelodysplastic Syndromes 26Recurrence 25Lymphoma, Non-Hodgkin 24Neoplasms 21Leukemia, Lymphocytic, Chronic, B-Cell 19Lymphoma, Large B-Cell, Diffuse 15Leukemia 12Lymphoma, Follicular 10Multiple Myeloma 9Hematologic Neoplasms 9Lymphoma, B-Cell, Marginal Zone 8Burkitt Lymphoma 7Lymphoma, Mantle-Cell 6Lymphoma, B-Cell 6Lymphoma 6Leukemia, Myelomonocytic, Chronic 6Leukemia, Myeloid 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Neoplasm Metastasis 4Myeloproliferative Disorders 4Leukemia, Biphenotypic, Acute 4Small Cell Lung Carcinoma 3Prostatic Neoplasms 3GATA2 Deficiency 3Carcinoma, Non-Small-Cell Lung 3Breast Neoplasms 3Primary Myelofibrosis 2Immunoglobulin Light-chain Amyloidosis 2Colorectal Neoplasms 2

Interventions

Cisplatin 21Etoposide 20Carboplatin 20Topotecan 13pembrolizumab 12durvalumab 11Paclitaxel 10Irinotecan 9Nivolumab 7Gemcitabine 7tremelimumab 6atezolizumab 6Radiotherapy 6Docetaxel 6Pemetrexed 5Ipilimumab 5Cyclophosphamide 5rovalpituzumab tesirine 4budigalimab 4Specimen Handling 4Injections 4Doxorubicin 4Bortezomib 4130-nm albumin-bound paclitaxel 4venetoclax 3talazoparib 3olaparib 3fludarabine 3etoposide phosphate 3Platinum 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × Small Cell Lung Carcinoma × venetoclax × Clear all
NCT03000257 2022-04-14

A Study of Budigalimab (ABBV-181) in Participants With Advanced Solid Tumors

AbbVie

Phase 1 Completed
182 enrolled
BreastDermatologicGastrointestinalGynecologicHead & NeckOther solid neoplasmThoracic

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Mesothelioma, Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Carcinoma, Merkel Cell, Cholangiocarcinoma, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT04422210 2021-11-08

A Study Evaluating The Safety, Tolerability, Pharmacokinetics, And Efficacy Of Venetoclax In Combination With Atezolizumab, Carboplatin, And Etoposide In Participants With Untreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC).

Hoffmann-La Roche

Phase 1 Terminated
2 enrolled
Thoracic

Small Cell Lung Carcinoma

NCT02391480 2019-11-29

A Study Evaluating the Safety and Pharmacokinetics of ABBV-075 in Subjects With Cancer

AbbVie

Phase 1 Completed
128 enrolled
BreastGenitourinaryLymphoidOther hematologic neoplasmPlasma cellThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lymphoma, Non-Hodgkin, Multiple Myeloma, Neoplasms, Prostatic Neoplasms, Leukemia, Myeloid, Acute, Small Cell Lung Carcinoma

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