Clinical Trials

Phase 1/2 Active not recruiting

Lung Neoplasms, Neoplasms, Small Cell Lung Carcinoma

NCT05616624 2026-04-15

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

31 enrolled

Phase 2 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma

NCT03540420 2026-04-13

ACHILES

212 enrolled

Phase 2 Active not recruiting

Small Cell Lung Carcinoma

NCT06227546 2026-04-13

MGC018-SCLC

9 enrolled 8 charts

Small Cell Lung Carcinoma

NCT07501169 2026-04-13

STAR-01

33 enrolled

Small Cell Lung Carcinoma

NCT07339059 2026-04-09

Phase II Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer

35 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT04919382 2026-04-08

Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

56 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT05903092 2026-04-07

MOZART

Phase 2 Suspended

84 enrolled

Phase NA Active not recruiting

Small Cell Lung Carcinoma

NCT05703269 2026-04-06

HYPOGRYPHE

58 enrolled

BreastCNSDermatologicGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Small Cell Lung Carcinoma

NCT04804644 2026-04-03

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Phase 3 Recruiting

200 enrolled

Brain Neoplasms, Lung Neoplasms, Small Cell Lung Carcinoma

NCT05957510 2026-04-03

Safety and Efficacy Evaluation of Serplulimab Plus Chemo in SCLC Transformed From EGFR-mutated NSCLC After Treatment

36 enrolled

Small Cell Lung Carcinoma

NCT07509333 2026-04-03

MDT-Based Umbrella Decision Model for Geriatric Lung Cancer Patients

Phase NA Recruiting

2,000 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT06840704 2026-04-02

Relief

Phase 3 Recruiting

121 enrolled

Carcinoma, Non-Small-Cell Lung, Esophagitis, Small Cell Lung Carcinoma

NCT07508852 2026-04-02

68Ga-PFD3 PET Imaging for the Diagnosis and Evaluation of Small Cell Lung Cancer

Phase 1/2 Recruiting

Phase 1 Active not recruiting

Disease, Small Cell Lung Carcinoma

NCT03923270 2026-04-01

Radiotherapy and Durvalumab/Durvalumab Combo (Tremelimumab/Olaparid) for Small Cell Lung Cancer

25 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT06807632 2026-04-01

A Study of Valemetostat in Combination With Atezolizumab in People With Lung Cancer

Phase 1 Recruiting

24 enrolled

Small Cell Lung Carcinoma

NCT07015892 2026-03-31

ESCALADOR

Phase 3 Recruiting

300 enrolled

Small Cell Lung Carcinoma

NCT05578326 2026-03-30

Study of Trilaciclib and Lurbinectidin

Lung Neoplasms, Neutropenia, Small Cell Lung Carcinoma

NCT06424067 2026-03-30

Phase 2 Study of Fingolimod in Lung Cancers

38 enrolled

Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma

NCT07489339 2026-03-30

SCLC-MDT

Phase NA Completed

200 enrolled

Phase NA Active not recruiting

Treatment Adherence and Compliance, Lung Neoplasms, Small Cell Lung Carcinoma

NCT04450043 2026-03-27

The Transitions Project: Supporting Adults During the Shift From Cancer Treatment to Surveillance

21 enrolled

Other solid neoplasmThoracic

Carcinoma, Non-Small-Cell Lung, Mesothelioma, Small Cell Lung Carcinoma

NCT06957314 2026-03-27

A Study of Hospital-at-Home for People Receiving Tarlatamab

Phase NA Recruiting

70 enrolled

Small Cell Lung Carcinoma

NCT07055581 2026-03-27

Durvalumab as Consolidation for Patients LS-SCLC

100 enrolled

Phase 4 Not yet recruiting

Small Cell Lung Carcinoma

NCT07485920 2026-03-20

A Prospective, Multicenter Exploratory Clinical Study on Consolidation Therapy With Tislelizumab Combined With Nintedanib for Limited-stage Small Cell Lung Cancer

20 enrolled

Small Cell Lung Carcinoma

NCT07001995 2026-03-16

Limertinib Plus Carboplatin and Etoposide for EGFR-mutant NSCLC With SCLC Transformation After EGFR-TKI Progression

Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma

NCT04170946 2026-03-05

Talazoparib

Phase 1 Recruiting

24 enrolled

Phase 2 Active not recruiting

Lung Neoplasms, Small Cell Lung Carcinoma

NCT04516070 2026-03-05

Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis

55 enrolled

Phase 1 Active not recruiting

Brain Neoplasms, Lung Neoplasms, Small Cell Lung Carcinoma

NCT03223155 2026-03-04

COSINR

78 enrolled

Small Cell Lung Carcinoma

NCT05068232 2026-03-04

Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES)

49 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT07402343 2026-03-04

T-BRAIN

34 enrolled

Brain Neoplasms, Small Cell Lung Carcinoma

NCT06719700 2026-03-03

Concurrent Chemoradiotherapy Combined With Toripalimab and Surufatinib in the Treatment of Limited-Stage Small Cell Lung Cancer

47 enrolled

Small Cell Lung Carcinoma

NCT07219251 2026-03-03

EVLC

Phase NA Recruiting

194 enrolled

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms, Small Cell Lung Carcinoma

NCT06830694 2026-02-23

Clinical Trial for Safety and Effectiveness Evaluation of Tarlatamab (AMG757) With Etoposide, Carboplatin and Atezolizumab in Transformed Small Cell Lung Cancer Patients From Adenocarcinoma After EGFR TKI Treatment

50 enrolled

Small Cell Lung Carcinoma

NCT07423585 2026-02-20

Tarlatamab for the Treatment of Extensive Stage Small-cell Lung Cancer

39 enrolled

Small Cell Lung Carcinoma

NCT05403723 2026-02-19

Adaptive SBRT Plus Chemoimmunotherapy for ES-SCLC

Phase 1 Suspended

50 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT07149363 2026-02-17

Adjuvant Chemotherapy and Immunotherapy for Completely Resected Small Cell Lung Cancer

65 enrolled

Phase 1/2 Active not recruiting

Small Cell Lung Carcinoma

NCT03830918 2026-02-12

Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy

59 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT05419076 2026-02-11

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

62 enrolled

Brain Neoplasms, Lung Neoplasms, Small Cell Lung Carcinoma

NCT07398560 2026-02-10

Adebrelimab Combined With Oral Etoposide for Elderly Patients and Patients With Poor Performance Status in Small Cell Lung Cancer: An Exploratory Clinical Study

47 enrolled

Phase NA Enrolling by invitation

Small Cell Lung Carcinoma

NCT07390565 2026-02-09

YSQTG Combined With Immuno-chemotherapy for Extensive-Stage Small Cell Lung Cancer

308 enrolled

Phase EARLY_PHASE1 Recruiting

Small Cell Lung Carcinoma

NCT05620342 2026-02-05

Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer

24 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT07388875 2026-02-05

SKB264-ANLO

Small Cell Lung Carcinoma

NCT07242547 2026-02-04

MERLIN

37 enrolled

Phase NA Not yet recruiting

Carcinoma, Non-Small-Cell Lung, Respiratory Tract Neoplasms, Thoracic Neoplasms, Small Cell Lung Carcinoma

NCT07383454 2026-02-03

Lung Cancer Screening in Population Who Had Never Smoked

2,500 enrolled

Carcinoma, Non-Small-Cell Lung, Disease, Lung Neoplasms, Small Cell Lung Carcinoma

NCT07376499 2026-01-29

Prospective, Single-arm, Phase II Clinical Study of Irinotecan Hydrochloride Liposome Injection Combined With Platinum and Immune Checkpoint Inhibitors Combined With Anlotinib for the Maintenance of Extensive Small Cell Lung Cancer After First-line Induction

31 enrolled

Small Cell Lung Carcinoma

NCT05223647 2026-01-28

TRIPLEX

Phase 3 Terminated

239 enrolled

Neoplasms, Small Cell Lung Carcinoma

NCT07373964 2026-01-28

A Prospective, Single-Arm, Single-Center Phase II Study Evaluating the Efficacy and Safety of Chidamide Combined With PD-L1 Inhibitor, Carboplatin, and Etoposide as First-Line Treatment in Patients With Extensive-Stage Small-Cell Lung Cancer (ES-SCLC)

36 enrolled

Small Cell Lung Carcinoma

NCT07357532 2026-01-22

Exploration of Treatment Strategies After Concurrent Chemoradiotherapy for LS-SCLC Guided by MRD

44 enrolled

Small Cell Lung Carcinoma

NCT07358676 2026-01-22

A Study of Bemotuzumab Plus Chemotherapy and Anlotinib Induction Followed by Bemotuzumab, Anlotinib and Consolidative Thoracic Radiotherapy in Extensive-Stage Small Cell Lung Cancer

25 enrolled