Announcements Trials
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Phase

Phase 3 2Phase 2 2

Status

Recruiting 1Not yet recruiting 1Completed 1Active not recruiting 1

Sponsor Class

INDUSTRY 2OTHER 1NETWORK 1

Study Type

Interventional 4

Sponsor

Cancer Type

Plasma cell 4

Conditions

Multiple Myeloma 123Recurrence 12Neoplasms 8Immunoglobulin Light-chain Amyloidosis 7Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 6Neoplasms, Plasma Cell 5Smoldering Multiple Myeloma 4Lymphoma 4Leukemia, Myeloid, Acute 4Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma, Non-Hodgkin 3Leukemia, Lymphocytic, Chronic, B-Cell 3Plasmacytoma 2Plasmablastic Lymphoma 2Neoplasm, Residual 2Myelodysplastic Syndromes 2Hodgkin Disease 2Hematologic Neoplasms 2Amyloidosis 2Acute Kidney Injury 2Triple Negative Breast Neoplasms 1Proteostasis Deficiencies 1Primary Myelofibrosis 1Paraproteinemias 1Non-small Cell Lung Cancer With STK11/LKB1 Mutation 1Microsatellite Unstable Colorectal Cancer 1Lymphoma, T-Cell, Peripheral 1Lymphoma, Large B-Cell, Diffuse 1Leukemia, Plasma Cell 1Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1

Interventions

Lenalidomide 7Dexamethasone 5daratumumab 4Calcium Dobesilate 4dexamethasone acetate 3dexamethasone 21-phosphate 3auricularum 3Curcumin 3isatuximab 2iberdomide 2Leflunomide 2pomalidomide 1poly ICLC 1piperine 1pembrolizumab 1ixazomib 1fludarabine phosphate 1fludarabine 1citarinostat 1Watchful Waiting 1Urination 1Stem Cell Transplantation 1Resistance Training 1Propranolol 1Probiotics 1Peripheral Blood Stem Cell Transplantation 1PVX-410 vaccine 1Observation 1Metformin 1Melphalan 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Smoldering Multiple Myeloma × daratumumab × 1 year × Clear all
NCT03937635 2026-05-15

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Eastern Cooperative Oncology Group

Phase 3 Recruiting
288 enrolled
Plasma cell

Smoldering Multiple Myeloma

NCT02316106 2026-04-23

A Study to Evaluate 3 Dose Schedules of Daratumumab in Participants With Smoldering Multiple Myeloma

Janssen Research & Development, LLC

Phase 2 Completed
123 enrolled 21 charts
Plasma cell

Smoldering Multiple Myeloma, Multiple Myeloma

NCT03236428 2026-03-27

Phase II Study of the CD38 Antibody Daratumumab in Patients With High-Risk MGUS and Low-Risk Smoldering Multiple Myeloma

Dana-Farber Cancer Institute

Phase 2 Active not recruiting
42 enrolled 8 charts
Plasma cell

Smoldering Multiple Myeloma, Paraproteinemias

NCT07393282 2026-03-16

LINKER-SMM2

Regeneron Pharmaceuticals

Phase 3 Not yet recruiting
270 enrolled
Plasma cell

Smoldering Multiple Myeloma, Multiple Myeloma

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