Announcements Trials
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Phase

Phase 3 2Phase 2 2

Status

Recruiting 1Not yet recruiting 1Completed 1Active not recruiting 1

Sponsor Class

INDUSTRY 2OTHER 1NETWORK 1

Study Type

Interventional 4

Sponsor

Cancer Type

Plasma cell 4

Conditions

Multiple Myeloma 68Recurrence 7Smoldering Multiple Myeloma 4Neoplasms 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Plasmablastic Lymphoma 2Lymphoma 2Leukemia, Myeloid, Acute 2Immunoglobulin Light-chain Amyloidosis 2Plasmacytoma 1Paraproteinemias 1Neoplasms, Plasma Cell 1Myelodysplastic Syndromes 1Lymphoma, Large B-Cell, Diffuse 1Leukemia, Plasma Cell 1Glioblastoma 1Carcinoma, Non-Small-Cell Lung 1

Interventions

daratumumab 4Lenalidomide 3dexamethasone acetate 2dexamethasone 21-phosphate 2auricularum 2Dexamethasone 2Curcumin 2Calcium Dobesilate 2piperine 1isatuximab 1iberdomide 1Watchful Waiting 1Stem Cell Transplantation 1Peripheral Blood Stem Cell Transplantation 1Observation 1Melphalan 1Leflunomide 1IPH-2101 1Dietary Fiber 1Diet, Mediterranean 1Cholestyramine Resin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Smoldering Multiple Myeloma × daratumumab × 90 days × Clear all
NCT03937635 2026-05-15

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Eastern Cooperative Oncology Group

Phase 3 Recruiting
288 enrolled
Plasma cell

Smoldering Multiple Myeloma

NCT02316106 2026-04-23

A Study to Evaluate 3 Dose Schedules of Daratumumab in Participants With Smoldering Multiple Myeloma

Janssen Research & Development, LLC

Phase 2 Completed
123 enrolled 21 charts
Plasma cell

Smoldering Multiple Myeloma, Multiple Myeloma

NCT03236428 2026-03-27

Phase II Study of the CD38 Antibody Daratumumab in Patients With High-Risk MGUS and Low-Risk Smoldering Multiple Myeloma

Dana-Farber Cancer Institute

Phase 2 Active not recruiting
42 enrolled 8 charts
Plasma cell

Smoldering Multiple Myeloma, Paraproteinemias

NCT07393282 2026-03-16

LINKER-SMM2

Regeneron Pharmaceuticals

Phase 3 Not yet recruiting
270 enrolled
Plasma cell

Smoldering Multiple Myeloma, Multiple Myeloma

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