Announcements Trials
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Phase

Phase 2 3Phase 3 2

Status

Active not recruiting 2Recruiting 1Not yet recruiting 1Completed 1

Sponsor Class

OTHER 2INDUSTRY 2NETWORK 1

Study Type

Interventional 5

Sponsor

Cancer Type

Plasma cell 5

Conditions

Multiple Myeloma 218Recurrence 27Neoplasms, Plasma Cell 15Neoplasms 13Immunoglobulin Light-chain Amyloidosis 13Leukemia, Myeloid, Acute 9Lymphoma, Non-Hodgkin 7Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 6Smoldering Multiple Myeloma 5Lymphoma 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Neoplasm, Residual 4Hematologic Neoplasms 4Plasmacytoma 3Paraproteinemias 3Myelodysplastic Syndromes 3Leukemia, Plasma Cell 3Leukemia, Lymphocytic, Chronic, B-Cell 3Hodgkin Disease 3Hematologic Diseases 3Carcinoma, Non-Small-Cell Lung 3Amyloidosis 3Waldenstrom Macroglobulinemia 2Triple Negative Breast Neoplasms 2Prostatic Neoplasms 2Plasmablastic Lymphoma 2Lymphoma, Large B-Cell, Diffuse 2Disease 2Corneal Diseases 2Blood Protein Disorders 2

Interventions

Lenalidomide 17Dexamethasone 15Calcium Dobesilate 8daratumumab 5dexamethasone acetate 4dexamethasone 21-phosphate 4carfilzomib 4auricularum 4Melphalan 4Leflunomide 3Curcumin 3isatuximab 2iberdomide 2elotuzumab 2Peripheral Blood Stem Cell Transplantation 2PVX-410 vaccine 2Denosumab 2Cyclophosphamide 2Bortezomib 2siltuximab 1selinexor 1sargramostim 1pomalidomide 1poly ICLC 1piperine 1pembrolizumab 1ixazomib 1ibrutinib 1fludarabine phosphate 1fludarabine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Smoldering Multiple Myeloma × daratumumab × Clear all
NCT03937635 2026-05-15

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Eastern Cooperative Oncology Group

Phase 3 Recruiting
288 enrolled
Plasma cell

Smoldering Multiple Myeloma

NCT02316106 2026-04-23

A Study to Evaluate 3 Dose Schedules of Daratumumab in Participants With Smoldering Multiple Myeloma

Janssen Research & Development, LLC

Phase 2 Completed
123 enrolled 21 charts
Plasma cell

Smoldering Multiple Myeloma, Multiple Myeloma

NCT03236428 2026-03-27

Phase II Study of the CD38 Antibody Daratumumab in Patients With High-Risk MGUS and Low-Risk Smoldering Multiple Myeloma

Dana-Farber Cancer Institute

Phase 2 Active not recruiting
42 enrolled 8 charts
Plasma cell

Smoldering Multiple Myeloma, Paraproteinemias

NCT07393282 2026-03-16

LINKER-SMM2

Regeneron Pharmaceuticals

Phase 3 Not yet recruiting
270 enrolled
Plasma cell

Smoldering Multiple Myeloma, Multiple Myeloma

NCT03289299 2023-12-12

ASCENT

International Myeloma Foundation

Phase 2 Active not recruiting
87 enrolled
Plasma cell

Smoldering Multiple Myeloma, Neoplasms, Plasma Cell

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