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Solid Tumors

NCT02597036 2025-10-23

A Study of LY3127804 With Ramucirumab in Participants With Advanced Solid Tumors

Phase 1 Terminated

62 enrolled 25 charts

Other solid neoplasm

Solid Tumors

NCT05976334 2025-10-06

An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors

Phase 1 Terminated

3 enrolled 19 charts

Other solid neoplasm

Solid Tumors

NCT04642365 2025-05-21

A Study to Evaluate the Safety and Tolerability of RO7296682 in Combination With Atezolizumab in Participants With Advanced Solid Tumors.

Phase 1 Terminated

49 enrolled 31 charts

Other solid neoplasm

Solid Tumors

NCT02240238 2025-01-22

Combination Therapy With NC-6004 and Gemcitabine in Advanced Solid Tumors or Non-Small Cell Lung, Biliary and Bladder Cancer

Phase 1/2 Completed

119 enrolled 24 charts

Other solid neoplasm

Solid Tumors

NCT03477175 2025-01-07

Study to Assess the Long-term Safety of Lenvatinib Monotherapy, a Lenvatinib Combination Regimen, or a Comparator Treatment Arm to Cancer Participants in Eisai Sponsored Lenvatinib Trials

Phase 2 Completed

40 enrolled 13 charts

Other solid neoplasm

Solid Tumors

NCT00828919 2024-12-03

Continuing Access to Axitinib (A406- AG- 013736 ) For Patients Previously Receiving AG 013736 In Clinical Trials

Phase NA Completed

52 enrolled 12 charts

Other solid neoplasm

Solid Tumors

NCT02699515 2024-11-18

MSB0011359C (M7824) in Participants With Metastatic or Locally Advanced Solid Tumors

Phase 1 Completed

114 enrolled 29 charts

Other solid neoplasm

Solid Tumors

NCT01127178 2024-10-10

Study of Poly (ADP-Ribose) Polymerase (PARP) Inhibitor E7016 in Combination With Temozolomide in Subjects With Advanced Solid Tumors

Phase 1 Terminated

12 enrolled 13 charts

Other solid neoplasm

Solid Tumors

NCT01286467 2024-03-06

A Study Of PF-04449913 Administered Alone In Select Solid Tumors

Phase 1 Completed

23 enrolled 26 charts

Other solid neoplasm

Solid Tumors

NCT04158583 2024-03-04

A Study to Evaluate the Safety and Tolerability of RO7296682 in Participants With Advanced Solid Tumors

Phase 1 Terminated

76 enrolled 30 charts

Other solid neoplasm

Solid Tumors

NCT01190644 2023-11-29

Study to Evaluate Effect of a Single Dose of Sotatercept (ACE-011) on Red Blood Cell Mass and Plasma Volume in Participants With Solid Tumors

Phase 2 Terminated

5 enrolled 11 charts

Other solid neoplasm

Solid Tumors

NCT03225105 2023-11-22

M3541 in Combination With Radiotherapy in Solid Tumors

Phase 1 Terminated

15 enrolled 18 charts

Other solid neoplasm

Solid Tumors

NCT00648648 2023-09-21

MK-1775-001

Phase 1 Completed

206 enrolled 40 charts

Other solid neoplasm

Solid Tumors

NCT02426892 2023-04-18

Nivolumab and HPV-16 Vaccination in Patients With HPV-16 Positive Incurable Solid Tumors

Phase 2 Completed

33 enrolled 14 charts

Other solid neoplasm

Solid Tumors

NCT02598960 2023-03-06

An Investigational Immuno-therapy Study of Experimental Medication BMS-986156, Given by Itself or in Combination With Nivolumab in Patients With Solid Cancers or Cancers That Have Spread.

Phase 1/2 Completed

295 enrolled 28 charts

Other solid neoplasm

Solid Tumors

NCT02593786 2022-10-24

CheckMate 077

Phase 1/2 Completed

58 enrolled 31 charts

Other solid neoplasm

Solid Tumors

NCT02639546 2022-09-16

iMATRIXcobi

Phase 1/2 Completed

56 enrolled 31 charts

Other solid neoplasm

Solid Tumors

NCT02660034 2021-12-06

The Safety, Pharmacokinetics and Antitumor Activity of BGB-A317 in Combination With BGB-290 in Participants With Advanced Solid Tumors

Phase 1 Completed

229 enrolled 46 charts

Other solid neoplasm

Solid Tumors

NCT01748825 2021-07-26

AZD1775 for Advanced Solid Tumors

Phase 1 Completed

67 enrolled 24 charts

Other solid neoplasm

Solid Tumors

NCT02533674 2021-06-11

Multicenter, Open-label, Clinical and Pharmacokinetic Study of PM060184 in Combination With Gemcitabine in Selected Patients With Advanced Solid Tumors

Phase 1 Completed

57 enrolled 19 charts

Other solid neoplasm

Solid Tumors

NCT03264066 2021-05-11

A Study to Investigate the Efficacy and Safety of Cobimetinib Plus Atezolizumab in Participants With Solid Tumors

Phase 2 Completed

87 enrolled 24 charts

Other solid neoplasm

Solid Tumors

NCT02587962 2021-01-14

Dose-escalation Study of Birinapant and Pembrolizumab in Solid Tumors

Phase 1/2 Terminated

34 enrolled 27 charts

Other solid neoplasm

Solid Tumors

NCT01943461 2020-09-30

Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor JPN)

Phase 1 Completed

57 enrolled 30 charts

Other solid neoplasm

Solid Tumors

NCT03539484 2020-09-03

A Study of RO7172508 in Patients With Locally Advanced and/or Metastatic CEA-Positive Solid Tumors

Phase 1 Terminated

26 enrolled 30 charts

Other solid neoplasm

Solid Tumors

NCT01369433 2020-09-01

A Rollover Protocol to Allow Continued Access to Tivozanib (AV 951) for Subjects Enrolled in Other Tivozanib Protocols

Phase NA Terminated

225 enrolled 7 charts

Other solid neoplasm

Solid Tumors

NCT01832506 2020-08-06

A Japanese Phase 1 Trial of c-Met Inhibitor MSC2156119J in Subjects With Solid Tumors

Phase 1 Completed

12 enrolled 17 charts

Other solid neoplasm

Solid Tumors

NCT01525602 2020-07-16

Safety Study of PLX3397 and Paclitaxel in Patients With Advanced Solid Tumors

Phase 1 Completed

74 enrolled 22 charts

Other solid neoplasm

Solid Tumors

NCT01862328 2020-06-22

Dose Escalation, Multi-arm Study of MLN4924 Plus Docetaxel, Gemcitabine, or Combination of Carboplatin and Paclitaxel in Participants With Solid Tumors

Phase 1 Completed

64 enrolled 21 charts

Other solid neoplasm

Solid Tumors

NCT01345513 2020-03-23

Feasibility Clinical Study of Targeted and Genome-Wide Sequencing

Completed

50 enrolled 8 charts

Other solid neoplasm

Solid Tumors

NCT02451007 2019-11-19

Evaluation of the Effect of Lurbinectedin (PM01183) on Cardiac Repolarization in Patients With Selected Solid Tumors

Phase 2 Completed

39 enrolled 11 charts

Other solid neoplasm

Solid Tumors

NCT01215916 2019-03-15

A Phase 1 Study in Patients With Solid Tumors

Phase 1 Completed

39 enrolled 18 charts

Other solid neoplasm

Solid Tumors

NCT01341457 2019-03-01

A Study of LY2603618 in Combination With Gemcitabine in Participants With Solid Tumors

Phase 1 Completed

17 enrolled 16 charts

Other solid neoplasm

Solid Tumors

NCT01431534 2019-03-01

MK-8669-056

Phase 1 Terminated

20 enrolled 10 charts

Other solid neoplasm

Solid Tumors

NCT01634555 2019-02-26

A Study to Assess the Pharmacokinetics of Ramucirumab (IMC-1121B) in Combination With FOLFIRI

Phase 2 Completed

29 enrolled 12 charts

Other solid neoplasm

Solid Tumors

NCT01214668 2019-01-04

Dose-Escalation Study of LY573636-sodium and Liposomal Doxorubicin in Patients With Advanced Solid Tumors

Phase 1 Completed

31 enrolled 17 charts

Other solid neoplasm

Solid Tumors

NCT01463696 2018-08-27

Study of Safety and Pharmacokinetics of MK-8242 in Participants With Advanced Solid Tumors (P07650)

Phase 1 Terminated

48 enrolled 17 charts

Other solid neoplasm

Solid Tumors

NCT01955473 2017-08-23

Japanese Phase 1 Trial of Sym004 in Solid Tumors

Phase 1 Completed

51 enrolled 49 charts

Other solid neoplasm

Solid Tumors

NCT01624467 2016-07-25

A Study of Necitumumab Monotherapy and the QT/QTc Interval in Patient With Advanced Solid Tumors

Phase 2 Completed

75 enrolled 12 charts

Other solid neoplasm

Solid Tumors

NCT02063230 2016-07-21

To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects

Phase 1 Completed

32 enrolled 12 charts

Other solid neoplasm

Solid Tumors

NCT00658658 2016-05-18

Panitumumab in Children With Solid Tumors

Phase 1 Completed

31 enrolled 19 charts

Other solid neoplasm

Solid Tumors

NCT00798889 2013-01-21

Rollover Protocol for Prior SU011248 Protocols

Phase NA Completed

314 enrolled 6 charts

Other solid neoplasm

Solid Tumors

NCT00424632 2012-06-25

Phase 1 Study Of Aurora Kinase Inhibitor PF-03814735 In Patients With Advanced Solid Tumors

Phase 1 Completed

57 enrolled 12 charts

Other solid neoplasm

Solid Tumors

Clinical Trials

A Study to Find a Suitable Dose of BI 1821736 and Test Whether it Helps People With Advanced Cancer

A Study of LY3127804 With Ramucirumab in Participants With Advanced Solid Tumors

An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors

A Study to Evaluate the Safety and Tolerability of RO7296682 in Combination With Atezolizumab in Participants With Advanced Solid Tumors.

Combination Therapy With NC-6004 and Gemcitabine in Advanced Solid Tumors or Non-Small Cell Lung, Biliary and Bladder Cancer

Study to Assess the Long-term Safety of Lenvatinib Monotherapy, a Lenvatinib Combination Regimen, or a Comparator Treatment Arm to Cancer Participants in Eisai Sponsored Lenvatinib Trials

Continuing Access to Axitinib (A406- AG- 013736 ) For Patients Previously Receiving AG 013736 In Clinical Trials

MSB0011359C (M7824) in Participants With Metastatic or Locally Advanced Solid Tumors

Study of Poly (ADP-Ribose) Polymerase (PARP) Inhibitor E7016 in Combination With Temozolomide in Subjects With Advanced Solid Tumors

A Study Of PF-04449913 Administered Alone In Select Solid Tumors

A Study to Evaluate the Safety and Tolerability of RO7296682 in Participants With Advanced Solid Tumors

Study to Evaluate Effect of a Single Dose of Sotatercept (ACE-011) on Red Blood Cell Mass and Plasma Volume in Participants With Solid Tumors

M3541 in Combination With Radiotherapy in Solid Tumors

MK-1775-001

Nivolumab and HPV-16 Vaccination in Patients With HPV-16 Positive Incurable Solid Tumors

An Investigational Immuno-therapy Study of Experimental Medication BMS-986156, Given by Itself or in Combination With Nivolumab in Patients With Solid Cancers or Cancers That Have Spread.

CheckMate 077

iMATRIXcobi

The Safety, Pharmacokinetics and Antitumor Activity of BGB-A317 in Combination With BGB-290 in Participants With Advanced Solid Tumors

AZD1775 for Advanced Solid Tumors

Multicenter, Open-label, Clinical and Pharmacokinetic Study of PM060184 in Combination With Gemcitabine in Selected Patients With Advanced Solid Tumors

A Study to Investigate the Efficacy and Safety of Cobimetinib Plus Atezolizumab in Participants With Solid Tumors

Dose-escalation Study of Birinapant and Pembrolizumab in Solid Tumors

Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor JPN)

A Study of RO7172508 in Patients With Locally Advanced and/or Metastatic CEA-Positive Solid Tumors

A Rollover Protocol to Allow Continued Access to Tivozanib (AV 951) for Subjects Enrolled in Other Tivozanib Protocols

A Japanese Phase 1 Trial of c-Met Inhibitor MSC2156119J in Subjects With Solid Tumors

Safety Study of PLX3397 and Paclitaxel in Patients With Advanced Solid Tumors

Dose Escalation, Multi-arm Study of MLN4924 Plus Docetaxel, Gemcitabine, or Combination of Carboplatin and Paclitaxel in Participants With Solid Tumors

Feasibility Clinical Study of Targeted and Genome-Wide Sequencing

Evaluation of the Effect of Lurbinectedin (PM01183) on Cardiac Repolarization in Patients With Selected Solid Tumors

A Phase 1 Study in Patients With Solid Tumors

A Study of LY2603618 in Combination With Gemcitabine in Participants With Solid Tumors

MK-8669-056

A Study to Assess the Pharmacokinetics of Ramucirumab (IMC-1121B) in Combination With FOLFIRI

Dose-Escalation Study of LY573636-sodium and Liposomal Doxorubicin in Patients With Advanced Solid Tumors

Study of Safety and Pharmacokinetics of MK-8242 in Participants With Advanced Solid Tumors (P07650)

Japanese Phase 1 Trial of Sym004 in Solid Tumors

A Study of Necitumumab Monotherapy and the QT/QTc Interval in Patient With Advanced Solid Tumors

To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects

Panitumumab in Children With Solid Tumors

Rollover Protocol for Prior SU011248 Protocols

Phase 1 Study Of Aurora Kinase Inhibitor PF-03814735 In Patients With Advanced Solid Tumors