Clinical Trials
5 trialsNCT02056392 2015-11-09
To Assess the Effects of Single Oral Dose of Selumetinib [AZD6244; ARRY-142886] [Hyd-Sulfate]), on QTc Interval in Healthy Male Volunteers
AstraZeneca
Phase 1 Completed
NCT01931761 2015-06-30
Study Evaluating Absorption, Distribution, Metabolism and Excretion (ADME) of Single Dose [14C] Selumetinib in Volunteers
AstraZeneca
Phase 1 Completed
NCT02093728 2015-06-30
To Assess the Effect of Itraconazole and Fluconazole on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers
AstraZeneca
Phase 1 Completed
NCT01974349 2014-08-13
To Assess the Effect of Food on the Pharmacokinetics of Selumetinib (AZD6244; ARRY-142886) (Hyd-Sulfate) in Healthy Male Volunteers
AstraZeneca
Phase 1 Completed
NCT02046850 2014-04-29
To Assess the Effect of Rifampicin on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers
AstraZeneca
Phase 1 Completed