Announcements Trials
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Phase

Phase 1 3

Status

Completed 3

Sponsor Class

INDUSTRY 3

Study Type

Interventional 3

Sponsor

Cancer Type

Other solid neoplasm 3

Conditions

Solid Tumours 3Neoplasms 2Breast Neoplasms 2Stomach Neoplasms 1Papillary renal cell carcinoma, sporadic 1Head and Neck Neoplasms 1Carcinoma, Renal Cell 1Carcinoma, Non-Small-Cell Lung 1Carcinoma, Hepatocellular 1Adenocarcinoma 1

Interventions

AZD 6244 5GSK 1363089 3pazopanib 1molibresib 1ispinesib 1enzalutamide 1brigimadlin 1abiraterone 1Topotecan 1SLC-0111 1Rifampin 1Prednisone 1Omeprazole 1Moxifloxacin 1Midazolam 1Itraconazole 1Granisetron 1Fluconazole 1Famotidine 1Doxorubicin 1Cytochrome P-450 CYP3A 1Cytochrome P-450 CYP2C19 1Cytochrome P-450 CYP1A2 1Carboplatin 1Carbon-14 1Caffeine 1CH5183284 1BGC945 12-((3-((4-((5-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)(ethyl)amino)ethyl dihydrogen phosphate 11-(1-(imidazo(1,2-a)pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-(1,2,3)triazolo(4,5-b)pyrazine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Interventional × Solid Tumours × GSK 1363089 × Clear all
NCT00742131 2017-07-31

A Dose Escalation Study of the Safety and Pharmacokinetics of GSK1363089 (Formerly XL880) Administered Orally to Subjects With Solid Tumors

GlaxoSmithKline

Phase 1 Completed
40 enrolled
Other solid neoplasm

Solid Tumours

NCT00743067 2017-07-26

A Dose Escalation Study of the Safety and Pharmacokinetics of GSK1363089 (Formerly XL880) Administered Orally Daily to Subjects With Solid Tumors

GlaxoSmithKline

Phase 1 Completed
37 enrolled
Other solid neoplasm

Solid Tumours

NCT00742261 2017-07-07

A Bioavailability Study of GSK1363089 in Subjects With Solid Tumors

GlaxoSmithKline

Phase 1 Completed
12 enrolled
Other solid neoplasm

Solid Tumours

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