Announcements Trials
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Phase

Phase 2 2Phase 3 1Phase 1/2 1

Status

Recruiting 2Active not recruiting 2

Sponsor Class

OTHER 3NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

Head & Neck 4

Conditions

Prostatic Neoplasms 7Brain Neoplasms 7Squamous Cell Carcinoma of Head and Neck 4Sarcoma 4Carcinoma, Non-Small-Cell Lung 4Solid Tumor, Adult 3Rhabdomyosarcoma 3Neoplasms 3Meningioma 3Glioma 3Esophageal Neoplasms 3Pituitary Neoplasms 2Osteosarcoma 2Nerve Sheath Neoplasms 2Glioblastoma 2Craniopharyngioma 2Chordoma 2Chondrosarcoma 2Breast Neoplasms 2Bone Neoplasms 2Wilms Tumor 1Vascular Neoplasms 1Stage I Prostate Adenocarcinoma AJCC v7 1Solitary Fibrous Tumors 1Solid Tumor 1Smooth Muscle Tumor 1Sarcoma, Ewing 1Sarcoma, Clear Cell 1Resectable Lung Non-Small Cell Carcinoma 1Recurrent Head and Neck Carcinoma 1

Interventions

pembrolizumab 137Cisplatin 75Cetuximab 51Carboplatin 49Paclitaxel 39Nivolumab 38Radiotherapy 37Docetaxel 34Radiotherapy, Intensity-Modulated 30Magnetic Resonance Spectroscopy 25Specimen Handling 20Fluorouracil 20Platinum 141,2-diaminocyclohexaneplatinum II citrate 13Taxes 12cemiplimab 11Radiation 11Ipilimumab 11atezolizumab 10Surgical Procedures, Operative 10Drug Therapy 10Biopsy 9durvalumab 8Radiosurgery 8130-nm albumin-bound paclitaxel 8tislelizumab 7Standard of Care 7Chemoradiotherapy 7Albumin-Bound Paclitaxel 7Immune Checkpoint Inhibitors 6

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Squamous Cell Carcinoma of Head and Neck × Proton Therapy × 1 year × Clear all
NCT04671667 2026-06-05

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

National Cancer Institute (NCI)

Phase 2 Recruiting
188 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT07213934 2026-04-15

Phase I/ II Trial Combining PD-1 Inhibition and Neoadjuvant Proton or Photon Radiation Therapy in Recurrent Head and Neck Squamous Cell Carcinoma

University of Cincinnati

Phase 1/2 Recruiting
40 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03323463 2026-04-13

Major De-escalation to 30 Gy for Select Human Papillomavirus Associated Oropharyngeal Carcinoma

Memorial Sloan Kettering Cancer Center

Phase 2 Active not recruiting
316 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT01893307 2026-02-24

Intensity-Modulated Proton Beam Therapy or Intensity-Modulated Photon Therapy in Treating Patients With Stage III-IVB Oropharyngeal Cancer

M.D. Anderson Cancer Center

Phase 3 Active not recruiting
440 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck

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