Announcements Trials
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Phase

Phase 2 2Phase 3 1

Status

Completed 2Terminated 1

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Head & Neck 3

Conditions

Pancreatic Neoplasms 4Uterine Cervical Neoplasms 3Squamous Cell Carcinoma of Head and Neck 3Carcinoma, Squamous Cell 3Rectal Neoplasms 2Head and Neck Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Carcinoma 2Adenocarcinoma Of Esophagus 2Tonsillar Neoplasms 1Resectable Esophageal Cancer 1Pharyngeal Neoplasms 1Neoplasms by Site 1Neoplasms 1Muscle Invasive Bladder Cancer 1Melanoma 1Lung Neoplasms 1Limited Stage Small Cell Lung Cancer 1Glioblastoma 1Esophageal Squamous Cell Carcinoma 1Esophageal Neoplasms 1Colorectal Neoplasms 1Carcinoma, Adenosquamous 1Brain Neoplasms 1Adenocarcinoma 1

Interventions

Cisplatin 76Cetuximab 60pembrolizumab 56Radiotherapy, Intensity-Modulated 37Radiotherapy 33Carboplatin 31Docetaxel 30Fluorouracil 27Nivolumab 26Paclitaxel 20Platinum 10Albumin-Bound Paclitaxel 9Surgical Procedures, Operative 8Radiosurgery 8Radiation 8Erlotinib Hydrochloride 8durvalumab 7Bevacizumab 71,2-diaminocyclohexaneplatinum II citrate 7epacadostat 6Biopsy 6Radiotherapy, Conformal 5Ipilimumab 5Immunoglobulin G 5Gemcitabine 5Capecitabine 5130-nm albumin-bound paclitaxel 5utomilumab 4tremelimumab 4palbociclib 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Has results × Squamous Cell Carcinoma of Head and Neck × Chemoradiotherapy × Clear all
NCT03107182 2025-05-06

OPTIMA-II

University of Chicago

Phase 2 Completed
72 enrolled 14 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT02207439 2023-07-25

Phase II Trial of Nelfinavir With Concurrent Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck

Abramson Cancer Center at Penn Medicine

Phase 2 Completed
18 enrolled 9 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT02952586 2021-09-22

Study To Compare Avelumab In Combination With Standard of Care Chemoradiotherapy (SoC CRT) Versus SoC CRT for Definitive Treatment In Patients With Locally Advanced Squamous Cell Carcinoma Of The Head And Neck (JAVELIN HEAD AND NECK 100)

Pfizer

Phase 3 Terminated
697 enrolled 26 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck

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